Norisoboldine, a Natural Isoquinoline Alkaloid, Inhibits Diaphyseal Fracture Healing in Mice by Alleviating Cartilage Formation

Norisoboldine, a Natural Isoquinoline Alkaloid, Inhibits Diaphyseal Fracture Healing in Mice by Alleviating Cartilage Formation

Norisoboldine (NOR), the major isoquinoline alkaloid constituent of a Chinese traditional medicine Radix Linderae, has been demonstrated to inhibit osteoclast differentiation and improve arthritis. The aim of this study is to examine the effect of NOR on bone fracture healing and the underlying mech...

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Bibliographic Details
Main Authors:	Wenliang Yan, Meng Shen, Kainong Sun, Shiming Li, Jingyuan Miao, Jun Wang, Jiayang Xu, Pengcheng Wen, Qian Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Series:	Biomedicines
Subjects:	norisoboldine fracture healing BMP2 endochondral ossification
Online Access:	https://www.mdpi.com/2227-9059/11/7/2031

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