Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease
Objective. To examine the relationships between measures of bone mineral density (BMD), coronary atherosclerosis, and coronary artery calcification among men with ischemic heart disease (IHD).Materials and Methods. Seventy-four men with angiographically documented IHD were assessed. BMD was measured...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2014-03-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/505 |
| _version_ | 1797876845120585728 |
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| author | Tat’yana Alekseyevna Raskina E B Malyuta O L Barbarash A N Kokov V L Masenko V A Voronkina |
| author_facet | Tat’yana Alekseyevna Raskina E B Malyuta O L Barbarash A N Kokov V L Masenko V A Voronkina |
| author_sort | Tat’yana Alekseyevna Raskina |
| collection | DOAJ |
| description | Objective. To examine the relationships between measures of bone mineral density (BMD), coronary atherosclerosis, and coronary artery calcification among men with ischemic heart disease (IHD).Materials and Methods. Seventy-four men with angiographically documented IHD were assessed. BMD was measured by dual-energy absorptiometry and defining the T-score, radiopaque selective coronary angiography with the analysis of severity of coronary artery lesions using the SYNTAX score, evaluating the coronary artery calcium score according to the Agatston method. Depending on the T-score, patients were divided into 2 groups: group I – patients with osteopenic syndrome (53 patients) aged 59 (52;68) years; group II – patients with normal BMD (21 patients) aged 58 (54;66 ) years.Results. Osteopenic syndrome among men with IHD was revealed in 71.6% of cases. Severe coronary lesions predominated among patients with osteopenic syndrome (p=0.041). Single-vessel coronary lesions in the group with osteopenic syndrome was detected less frequently than in the normal BMD (p=0.023) group. Calcium score values significantly correlated with the severity of coronary lesions according to the Syntax scale (r=0,53; p=0.002).Conclusion. Reduced bone mineral density among men is associated with hemodynamically significant lesion and correlates with the severity of coronary atherosclerosis, which confirms the likelihood of common pathogenesis of osteopenic syndrome and coronary artery atherosclerosis. |
| first_indexed | 2024-04-10T02:07:46Z |
| format | Article |
| id | doaj.art-a68c1559030749dc82ef7033ce3a3b1e |
| institution | Directory Open Access Journal |
| issn | 1996-7012 2310-158X |
| language | Russian |
| last_indexed | 2024-04-10T02:07:46Z |
| publishDate | 2014-03-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj.art-a68c1559030749dc82ef7033ce3a3b1e2023-03-13T08:39:23ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2014-03-0181182210.14412/1996-7012-2014-1-18-221810Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart diseaseTat’yana Alekseyevna Raskina0E B Malyuta1O L Barbarash2A N Kokov3V L Masenko4V A Voronkina5кафедра пропедевтики внутренних болезней ГБОУ ВПО «Кемеровская государственная медицинская академия» Минздрава России, Кемерово, Россия; 650029, Кемерово, ул. Ворошилова, 22АМБУЗ «Городская клиническая больница № 3 им. М.А. Подгорбунского, Кемерово, Россия; 650099, Кемерово, ул. Островского, 22ФГБУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» СО РАМН, Кемерово, Россия; 650002, Кемерово, Сосновый бульвар, 6ФГБУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» СО РАМН, Кемерово, Россия; 650002, Кемерово, Сосновый бульвар, 6ФГБУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» СО РАМН, Кемерово, Россия; 650002, Кемерово, Сосновый бульвар, 6МБУЗ «Городская клиническая больница № 3 им. М.А. Подгорбунского, Кемерово, Россия; 650099, Кемерово, ул. Островского, 22Objective. To examine the relationships between measures of bone mineral density (BMD), coronary atherosclerosis, and coronary artery calcification among men with ischemic heart disease (IHD).Materials and Methods. Seventy-four men with angiographically documented IHD were assessed. BMD was measured by dual-energy absorptiometry and defining the T-score, radiopaque selective coronary angiography with the analysis of severity of coronary artery lesions using the SYNTAX score, evaluating the coronary artery calcium score according to the Agatston method. Depending on the T-score, patients were divided into 2 groups: group I – patients with osteopenic syndrome (53 patients) aged 59 (52;68) years; group II – patients with normal BMD (21 patients) aged 58 (54;66 ) years.Results. Osteopenic syndrome among men with IHD was revealed in 71.6% of cases. Severe coronary lesions predominated among patients with osteopenic syndrome (p=0.041). Single-vessel coronary lesions in the group with osteopenic syndrome was detected less frequently than in the normal BMD (p=0.023) group. Calcium score values significantly correlated with the severity of coronary lesions according to the Syntax scale (r=0,53; p=0.002).Conclusion. Reduced bone mineral density among men is associated with hemodynamically significant lesion and correlates with the severity of coronary atherosclerosis, which confirms the likelihood of common pathogenesis of osteopenic syndrome and coronary artery atherosclerosis.https://mrj.ima-press.net/mrj/article/view/505коронарный атеросклерозостеопороз: кальцификациямужчины |
| spellingShingle | Tat’yana Alekseyevna Raskina E B Malyuta O L Barbarash A N Kokov V L Masenko V A Voronkina Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease Современная ревматология коронарный атеросклероз остеопороз: кальцификация мужчины |
| title | Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| title_full | Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| title_fullStr | Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| title_full_unstemmed | Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| title_short | Relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| title_sort | relationship between the osteopenic syndrome and coronary artery disease in male patients with ischemic heart disease |
| topic | коронарный атеросклероз остеопороз: кальцификация мужчины |
| url | https://mrj.ima-press.net/mrj/article/view/505 |
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