Insights from the Genome Sequence of <italic toggle="yes">Mycobacterium lepraemurium</italic>: Massive Gene Decay and Reductive Evolution

Insights from the Genome Sequence of <italic toggle="yes">Mycobacterium lepraemurium</italic>: Massive Gene Decay and Reductive Evolution

ABSTRACT Mycobacterium lepraemurium is the causative agent of murine leprosy, a chronic, granulomatous disease similar to human leprosy. Due to the similar clinical manifestations of human and murine leprosy and the difficulty of growing both bacilli axenically, Mycobacterium leprae and M. lepraemur...

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Main Authors: Andrej Benjak, Tanvi P. Honap, Charlotte Avanzi, Enrique Becerril-Villanueva, Iris Estrada-García, Oscar Rojas-Espinosa, Anne C. Stone, Stewart T. Cole
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Subjects:
Mycobacterium lepraemurium
comparative genomics
genome sequencing
murine leprosy
Online Access:https://journals.asm.org/doi/10.1128/mBio.01283-17

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