Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents

Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents

Programmed cell death 1(PD-1)/programmed cell death ligand 1(PD-L1) have emerged as one of the most promising immune checkpoint targets for cancer immunotherapy. Despite the inherent advantages of small-molecule inhibitors over antibodies, the discovery of small-molecule inhibitors has fallen behind...

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Những tác giả chính: Chengliang Sun, Yao Cheng, Xiaojia Liu, Gefei Wang, Wenjian Min, Xiao Wang, Kai Yuan, Yi Hou, Jiaxing Li, Haolin Zhang, Haojie Dong, Liping Wang, Chenguang Lou, Yanze Sun, Xinmiao Yu, Hongbin Deng, Yibei Xiao, Peng Yang
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Elsevier 2022-12-01
Loạt:Acta Pharmaceutica Sinica B
Những chủ đề:
PD-1/PD-L1
Small-molecule inhibitor
Immunotherapy
Co-crystal structure
Truy cập trực tuyến:http://www.sciencedirect.com/science/article/pii/S2211383522001770

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http://www.sciencedirect.com/science/article/pii/S2211383522001770

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