PARP-1 Expression and <i>BRCA1</i> Mutations in Breast Cancer Patients’ CTCs

PARP-1 Expression and <i>BRCA1</i> Mutations in Breast Cancer Patients’ CTCs

<i>BRCA1</i> and PARP are involved in DNA damage repair pathways. <i>BRCA1</i> mutations have been linked to higher likelihood of triple negative breast cancer (TNBC). The aim of the study was to determine PARP-1 expression and <i>BRCA1</i> mutations in circulatin...

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Bibliographic Details
Main Authors: Thodoris Sklias, Vasileios Vardas, Evangelia Pantazaka, Athina Christopoulou, Vassilis Georgoulias, Athanasios Kotsakis, Yiannis Vasilopoulos, Galatea Kallergi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
PARP-1
<i>BRCA1</i>
circulating tumor cells
breast cancer
triple negative breast cancer
luminal
Online Access:https://www.mdpi.com/2072-6694/14/7/1731

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