Application of HPLC-QQQ-MS/MS and New RP-HPLC-DAD System Utilizing the Chaotropic Effect for Determination of Nicotine and Its Major Metabolites Cotinine, and <i>trans</i>-3′-Hydroxycotinine in Human Plasma Samples
The routine techniques currently applied for the determination of nicotine and its major metabolites, cotinine, and <i>trans</i>-3′-hydroxycotinine, in biological fluids, include spectrophotometric, immunoassays, and chromatographic techniques. The aim of this study was to develop, and c...
| Main Authors: | , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
MDPI AG
2022-01-01
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| 叢編: | Molecules |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/1420-3049/27/3/682 |