New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods

The simultaneous spectral prediction of levamisole (LEV) and triclabendazole (TRI) in combined veterinary formulation was performed by the new chemometric methods, artificial neural network (ANN) and principal component analysis-artificial neural network (PCA-ANN). Despite the overlapping spectra of...

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Main Authors: Dinç Erdal, Baleanu Dumitru, Köktaş Nigar Şen
Format: Article
Language:English
Published: De Gruyter 2011-04-01
Series:Reviews in Analytical Chemistry
Subjects:
Online Access:https://doi.org/10.1515/revac.2011.004
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author Dinç Erdal
Baleanu Dumitru
Köktaş Nigar Şen
author_facet Dinç Erdal
Baleanu Dumitru
Köktaş Nigar Şen
author_sort Dinç Erdal
collection DOAJ
description The simultaneous spectral prediction of levamisole (LEV) and triclabendazole (TRI) in combined veterinary formulation was performed by the new chemometric methods, artificial neural network (ANN) and principal component analysis-artificial neural network (PCA-ANN). Despite the overlapping spectra of LEV and TRI in the same wavelength region, the proposed methods do not use any separation procedure for the analysis of the related compounds. Good precision and accuracy were observed for the applications of the proposed artificial neural network models to an independent binary mixture set consisting of the active compounds. These methods were successfully applied for the chemometric quantitation of a veterinary formulation of LEV and TRI.
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spelling doaj.art-a6a24a57672d4d8aa342f5f47b27382e2022-12-21T18:38:17ZengDe GruyterReviews in Analytical Chemistry0793-01352191-01892011-04-01301111510.1515/revac.2011.004New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methodsDinç Erdal0Baleanu DumitruKöktaş Nigar Şen1Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100, Tandoğan, Ankara, TurkeyDepartment of Mathematics and Computer Sciences, Faculty of Arts and Sciences, Çankaya University, 06530 Balgat, Ankara, TurkeyThe simultaneous spectral prediction of levamisole (LEV) and triclabendazole (TRI) in combined veterinary formulation was performed by the new chemometric methods, artificial neural network (ANN) and principal component analysis-artificial neural network (PCA-ANN). Despite the overlapping spectra of LEV and TRI in the same wavelength region, the proposed methods do not use any separation procedure for the analysis of the related compounds. Good precision and accuracy were observed for the applications of the proposed artificial neural network models to an independent binary mixture set consisting of the active compounds. These methods were successfully applied for the chemometric quantitation of a veterinary formulation of LEV and TRI.https://doi.org/10.1515/revac.2011.004artificial neural networkslevamisoleprincipal component analysistriclabendazole
spellingShingle Dinç Erdal
Baleanu Dumitru
Köktaş Nigar Şen
New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
Reviews in Analytical Chemistry
artificial neural networks
levamisole
principal component analysis
triclabendazole
title New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
title_full New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
title_fullStr New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
title_full_unstemmed New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
title_short New spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ANN and PCA-ANN methods
title_sort new spectral approaches to the simultaneous quantitative resolution of a combined veterinary formulation by ann and pca ann methods
topic artificial neural networks
levamisole
principal component analysis
triclabendazole
url https://doi.org/10.1515/revac.2011.004
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AT baleanudumitru newspectralapproachestothesimultaneousquantitativeresolutionofacombinedveterinaryformulationbyannandpcaannmethods
AT koktasnigarsen newspectralapproachestothesimultaneousquantitativeresolutionofacombinedveterinaryformulationbyannandpcaannmethods