Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against <i>Mycobacterium tuberculosis</i>

Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against <i>Mycobacterium tuberculosis</i>

The development of novel pharmaceutical tools to efficiently tackle tuberculosis is the order of the day due to the rapid development of resistant strains of <i>Mycobacterium tuberculosis</i>. Herein, we report novel potential formulations of a repurposed drug, the antimalarial mefloquin...

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Bibliographic Details
Main Authors: Dário Silva, Márcio V. C. Lopes, Željko Petrovski, Miguel M. Santos, Jussevania P. Santos, Sueli F. Yamada-Ogatta, Marcelle L. F. Bispo, Marcus V. N. de Souza, Ana Rita C. Duarte, Maria C. S. Lourenço, Raoni Schroeder B. Gonçalves, Luis C. Branco
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
API-OSILs
ionic liquids
mefloquine
polymorphism
tuberculosis
Online Access:https://www.mdpi.com/1420-3049/27/16/5167

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