Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports?
Patients' unawareness of their cancer diagnosis (PUAW) and their tendency for non-disclosure (TTND) to relatives leads to a lack of cancer visibility among familial networks. Lack of familial cancer visibility could affect the accuracy of family cancer history (FCH) reports. In this study, we i...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4550411?pdf=render |
| _version_ | 1818209608317009920 |
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| author | Hossein Molavi Vardanjani Mohammad Reza Baneshi AliAkbar Haghdoost |
| author_facet | Hossein Molavi Vardanjani Mohammad Reza Baneshi AliAkbar Haghdoost |
| author_sort | Hossein Molavi Vardanjani |
| collection | DOAJ |
| description | Patients' unawareness of their cancer diagnosis (PUAW) and their tendency for non-disclosure (TTND) to relatives leads to a lack of cancer visibility among familial networks. Lack of familial cancer visibility could affect the accuracy of family cancer history (FCH) reports. In this study, we investigated familial cancer visibility and its potential determinants.A sample of patients with a confirmed cancer diagnosis was interviewed. Participants were asked about their number of relatives, number of their relatives who are aware about the cancer diagnosis, and the number of relatives from whom they intended to conceal their diagnosis. PUAW was also assessed. Point estimates and 95% confidence intervals were calculated using the bootstrap technique. Multivariate analyses were conducted using mixed Poisson and logistic regression analyses.A total of 415 participants with a mean age of 53±15 years and a male to female ratio of 0.53 were enrolled in this study. The rates of PUAW, TTND, and familial cancer visibility in the total sample were 0.20 (95% confidence interval (CI): 0.16, 0.24), 0.16 (95% CI: 0.12, 0.19), and 0.86 (95% CI: 0.83, 0.89), respectively. PUAW (adjusted rate ratio (RR) = 1.32, 95% CI: 1.27, 1.38), TTND (RR = 0.92, 95% CI: 0.91, 0.93), and the patients' gender (RR = 0.92, 95% CI: 0.82, 0.95) were the most important determinants of familial cancer visibility.Familial cancer visibility may be a point of concern among the Iranian population. Self-reported cancer histories and FCHs may have low sensitivities (not exceeding 80% and 86%, respectively) in this population. However, these estimates may vary across different societies, because of societal and cultural contexts. |
| first_indexed | 2024-12-12T05:03:25Z |
| format | Article |
| id | doaj.art-a6a5613b0e6a403c94522f1c87b1ab3e |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T05:03:25Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a6a5613b0e6a403c94522f1c87b1ab3e2022-12-22T00:37:10ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01108e013603810.1371/journal.pone.0136038Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports?Hossein Molavi VardanjaniMohammad Reza BaneshiAliAkbar HaghdoostPatients' unawareness of their cancer diagnosis (PUAW) and their tendency for non-disclosure (TTND) to relatives leads to a lack of cancer visibility among familial networks. Lack of familial cancer visibility could affect the accuracy of family cancer history (FCH) reports. In this study, we investigated familial cancer visibility and its potential determinants.A sample of patients with a confirmed cancer diagnosis was interviewed. Participants were asked about their number of relatives, number of their relatives who are aware about the cancer diagnosis, and the number of relatives from whom they intended to conceal their diagnosis. PUAW was also assessed. Point estimates and 95% confidence intervals were calculated using the bootstrap technique. Multivariate analyses were conducted using mixed Poisson and logistic regression analyses.A total of 415 participants with a mean age of 53±15 years and a male to female ratio of 0.53 were enrolled in this study. The rates of PUAW, TTND, and familial cancer visibility in the total sample were 0.20 (95% confidence interval (CI): 0.16, 0.24), 0.16 (95% CI: 0.12, 0.19), and 0.86 (95% CI: 0.83, 0.89), respectively. PUAW (adjusted rate ratio (RR) = 1.32, 95% CI: 1.27, 1.38), TTND (RR = 0.92, 95% CI: 0.91, 0.93), and the patients' gender (RR = 0.92, 95% CI: 0.82, 0.95) were the most important determinants of familial cancer visibility.Familial cancer visibility may be a point of concern among the Iranian population. Self-reported cancer histories and FCHs may have low sensitivities (not exceeding 80% and 86%, respectively) in this population. However, these estimates may vary across different societies, because of societal and cultural contexts.http://europepmc.org/articles/PMC4550411?pdf=render |
| spellingShingle | Hossein Molavi Vardanjani Mohammad Reza Baneshi AliAkbar Haghdoost Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? PLoS ONE |
| title | Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? |
| title_full | Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? |
| title_fullStr | Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? |
| title_full_unstemmed | Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? |
| title_short | Cancer Visibility among Iranian Familial Networks: To What Extent Can We Rely on Family History Reports? |
| title_sort | cancer visibility among iranian familial networks to what extent can we rely on family history reports |
| url | http://europepmc.org/articles/PMC4550411?pdf=render |
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