Neural Substrates of the Drift-Diffusion Model in Brain Disorders
Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Computational Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fncom.2021.678232/full |
| _version_ | 1818974601120579584 |
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| author | Ankur Gupta Rohini Bansal Hany Alashwal Anil Safak Kacar Fuat Balci Fuat Balci Ahmed A. Moustafa Ahmed A. Moustafa Ahmed A. Moustafa |
| author_facet | Ankur Gupta Rohini Bansal Hany Alashwal Anil Safak Kacar Fuat Balci Fuat Balci Ahmed A. Moustafa Ahmed A. Moustafa Ahmed A. Moustafa |
| author_sort | Ankur Gupta |
| collection | DOAJ |
| description | Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex and basal ganglia. Furthermore, we discuss the changes in DDM parameters due to structural and functional impairments in several clinical disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Obsessive-Compulsive Disorder (OCD), and schizophrenia. This review thus uses DDM to provide a theoretical understanding of different brain disorders. |
| first_indexed | 2024-12-20T15:42:39Z |
| format | Article |
| id | doaj.art-a6a749f25e8b45ffb35661bd5fc23f6c |
| institution | Directory Open Access Journal |
| issn | 1662-5188 |
| language | English |
| last_indexed | 2024-12-20T15:42:39Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Computational Neuroscience |
| spelling | doaj.art-a6a749f25e8b45ffb35661bd5fc23f6c2022-12-21T19:35:07ZengFrontiers Media S.A.Frontiers in Computational Neuroscience1662-51882022-01-011510.3389/fncom.2021.678232678232Neural Substrates of the Drift-Diffusion Model in Brain DisordersAnkur Gupta0Rohini Bansal1Hany Alashwal2Anil Safak Kacar3Fuat Balci4Fuat Balci5Ahmed A. Moustafa6Ahmed A. Moustafa7Ahmed A. Moustafa8CNRS UMR 5293, Institut des Maladies Neurodégénératives, Université de Bordeaux, Bordeaux, FranceDepartment of Medical Neurobiology, The Hebrew University of Jerusalem, Jerusalem, IsraelCollege of Information Technology, United Arab Emirates University, Al-Ain, United Arab EmiratesResearch Center for Translational Medicine (KUTTAM), Koç University, Istanbul, TurkeyResearch Center for Translational Medicine (KUTTAM), Koç University, Istanbul, TurkeyDepartment of Biological Sciences, University of Manitoba, Winnipeg, MB, CanadaSchool of Psychology & Marcs Institute for Brain and Behaviour, Western Sydney University, Sydney, NSW, AustraliaSchool of Psychology, Faculty of Society and Design, Bond University, Robina, QLD, AustraliaFaculty of Health Sciences, Department of Human Anatomy and Physiology, University of Johannesburg, Johannesburg, South AfricaMany studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex and basal ganglia. Furthermore, we discuss the changes in DDM parameters due to structural and functional impairments in several clinical disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Obsessive-Compulsive Disorder (OCD), and schizophrenia. This review thus uses DDM to provide a theoretical understanding of different brain disorders.https://www.frontiersin.org/articles/10.3389/fncom.2021.678232/fulldrift diffusion modelsdecision makingprefrontal cortexbasal ganglianeural mechanism |
| spellingShingle | Ankur Gupta Rohini Bansal Hany Alashwal Anil Safak Kacar Fuat Balci Fuat Balci Ahmed A. Moustafa Ahmed A. Moustafa Ahmed A. Moustafa Neural Substrates of the Drift-Diffusion Model in Brain Disorders Frontiers in Computational Neuroscience drift diffusion models decision making prefrontal cortex basal ganglia neural mechanism |
| title | Neural Substrates of the Drift-Diffusion Model in Brain Disorders |
| title_full | Neural Substrates of the Drift-Diffusion Model in Brain Disorders |
| title_fullStr | Neural Substrates of the Drift-Diffusion Model in Brain Disorders |
| title_full_unstemmed | Neural Substrates of the Drift-Diffusion Model in Brain Disorders |
| title_short | Neural Substrates of the Drift-Diffusion Model in Brain Disorders |
| title_sort | neural substrates of the drift diffusion model in brain disorders |
| topic | drift diffusion models decision making prefrontal cortex basal ganglia neural mechanism |
| url | https://www.frontiersin.org/articles/10.3389/fncom.2021.678232/full |
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