A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes

A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes

<p>Abstract</p> <p>Background</p> <p>The functional state of human telomeres is controlled by telomerase and by a protein complex named shelterin, including the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 involved in telomere capping functions. The expression of...

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Bibliographic Details
Main Authors: Gilson Eric, Gazzolo Louis, Belleville Aurélie, Roborel de Climens Aude, Rezza Amélie, Escoffier Emmanuelle, Duc Dodon Madeleine
Format: Article
Language:English
Published: BMC 2005-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/77

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