COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE

We present a case of successful combined treatment for dendritic stone (K-IY according to classification of Scientific Research Institute of Urology) in the left kidney of a patient with comorbid pathology (diabetes mellitus II type, CHI risk I, lumbar osteochondrosis). Feature of this case is that...

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Main Authors: V. L. Medvedev, A. S. Tatevosyan, G. D. Dmitrenko, S. S. Ryabokon, S. Z. Abiyan, A. A. Budanov, A. A. Leschinsky
Format: Article
Language:Russian
Published: Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 2019-03-01
Series:Инновационная медицина Кубани
Subjects:
Online Access:https://inovmed.elpub.ru/jour/article/view/153
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author V. L. Medvedev
A. S. Tatevosyan
G. D. Dmitrenko
S. S. Ryabokon
S. Z. Abiyan
A. A. Budanov
A. A. Leschinsky
author_facet V. L. Medvedev
A. S. Tatevosyan
G. D. Dmitrenko
S. S. Ryabokon
S. Z. Abiyan
A. A. Budanov
A. A. Leschinsky
author_sort V. L. Medvedev
collection DOAJ
description We present a case of successful combined treatment for dendritic stone (K-IY according to classification of Scientific Research Institute of Urology) in the left kidney of a patient with comorbid pathology (diabetes mellitus II type, CHI risk I, lumbar osteochondrosis). Feature of this case is that during operative transcutaneous endoscopic intervention we removed ≈80% of an easily available pelvic part of a stone, and to avoid excessive trauma of parenchymatous tissue for the purpose of the maximum preservation of renal function, we left intact hard to reach calyceal fragments of a concrement. Considering data of рН metric 3-day monitoring which revealed constantly sharp sour reaction of urine (<5.8–6.0), within the 5-month postoperative follow-up, the patient accepted health supplement ‘OMS-citrate’ according to the administered scheme which provides implementation of the maximum scope рН urine and individual dosage selection depending on the personified extent of metabolism disorder.The offered approach in citrate ‘mixtures’ administration deprives of a possibility for salts settling out, interfaced to the corresponding enzymes, as there are no conditions for incrustation of an external layer of a stone, as with a normal amplitude рН urine from 5.0 to 8.0 (>0 U), activity of all enzymes are reduced as their activation requires long (10–15 day) stay of рН urine in narrow limits (<0.8–1.2 units an isoaciduria). Citrate therapy in the setting of the stent of internal drainage, had been carried out, within 4 months the remained stone fragments completely released all renal collecting system, and on the stent after its extraction in 5 months there were no signs of salt incrustation. X-ray-radiological examinations in 1.5 years after the operation showed no signs of lithiasis recurrence, at the same time function of kidneys did not worsen (remained), and the urodynamics was restored. Besides, on the background of the carried-out treatment fornephrolithiasis, positive dynamics of the accompanying comorbid pathology (diabetes and atherosclerotic disease) was observed.
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spelling doaj.art-a6a9973134314600be800c40f2c561262022-12-22T03:29:50ZrusScientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1Инновационная медицина Кубани2500-02682541-98972019-03-01013643151COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASEV. L. Medvedev0A. S. Tatevosyan1G. D. Dmitrenko2S. S. Ryabokon3S. Z. Abiyan4A. A. Budanov5A. A. Leschinsky6Kuban State Medical University; Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Kuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Krasnodar Clinical Hospital of War VeteransRegional Clinical Hospital no. 2Kuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1We present a case of successful combined treatment for dendritic stone (K-IY according to classification of Scientific Research Institute of Urology) in the left kidney of a patient with comorbid pathology (diabetes mellitus II type, CHI risk I, lumbar osteochondrosis). Feature of this case is that during operative transcutaneous endoscopic intervention we removed ≈80% of an easily available pelvic part of a stone, and to avoid excessive trauma of parenchymatous tissue for the purpose of the maximum preservation of renal function, we left intact hard to reach calyceal fragments of a concrement. Considering data of рН metric 3-day monitoring which revealed constantly sharp sour reaction of urine (<5.8–6.0), within the 5-month postoperative follow-up, the patient accepted health supplement ‘OMS-citrate’ according to the administered scheme which provides implementation of the maximum scope рН urine and individual dosage selection depending on the personified extent of metabolism disorder.The offered approach in citrate ‘mixtures’ administration deprives of a possibility for salts settling out, interfaced to the corresponding enzymes, as there are no conditions for incrustation of an external layer of a stone, as with a normal amplitude рН urine from 5.0 to 8.0 (>0 U), activity of all enzymes are reduced as their activation requires long (10–15 day) stay of рН urine in narrow limits (<0.8–1.2 units an isoaciduria). Citrate therapy in the setting of the stent of internal drainage, had been carried out, within 4 months the remained stone fragments completely released all renal collecting system, and on the stent after its extraction in 5 months there were no signs of salt incrustation. X-ray-radiological examinations in 1.5 years after the operation showed no signs of lithiasis recurrence, at the same time function of kidneys did not worsen (remained), and the urodynamics was restored. Besides, on the background of the carried-out treatment fornephrolithiasis, positive dynamics of the accompanying comorbid pathology (diabetes and atherosclerotic disease) was observed.https://inovmed.elpub.ru/jour/article/view/153isoaciduriauratic dendritic nephrolithiasiscombined citrate therapy
spellingShingle V. L. Medvedev
A. S. Tatevosyan
G. D. Dmitrenko
S. S. Ryabokon
S. Z. Abiyan
A. A. Budanov
A. A. Leschinsky
COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
Инновационная медицина Кубани
isoaciduria
uratic dendritic nephrolithiasis
combined citrate therapy
title COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
title_full COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
title_fullStr COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
title_full_unstemmed COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
title_short COMBINED TREATMENT FOR DENDRITIC NEPHROLITHIASIS. CLINICAL CASE
title_sort combined treatment for dendritic nephrolithiasis clinical case
topic isoaciduria
uratic dendritic nephrolithiasis
combined citrate therapy
url https://inovmed.elpub.ru/jour/article/view/153
work_keys_str_mv AT vlmedvedev combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT astatevosyan combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT gddmitrenko combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT ssryabokon combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT szabiyan combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT aabudanov combinedtreatmentfordendriticnephrolithiasisclinicalcase
AT aaleschinsky combinedtreatmentfordendriticnephrolithiasisclinicalcase