DNA hypermethylation of Kiss1r promoter and reduction of hepatic Kiss1r in female rats with type 2 diabetes

DNA hypermethylation of Kiss1r promoter and reduction of hepatic Kiss1r in female rats with type 2 diabetes

Kisspeptin, produced from the brain and peripheral tissues, may constitute an important link in metabolic regulation in response to external cues, such as diet. The kisspeptin system is well described in the brain. However, its function and regulation in the peripheral tissues, especially in relatio...

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Bibliographic Details
Main Authors: Kamil Ziarniak, Tony Yang, Cayla Boycott, Megan Beetch, Maciej Sassek, Emilia Grzeda, Yuexi Ma, Joanna H. Sliwowska, Barbara Stefanska
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Epigenetics
Subjects:
dna methylation
kisspeptin
diabetes type 2
liver
Online Access:http://dx.doi.org/10.1080/15592294.2022.2119120

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