Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study
Abstract Purpose This study evaluated the regenerated cartilage after opening‐wedge high tibial osteotomy (OWHTO) with concomitant microfracture by second‐look arthroscopy, Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score and magnetic resonance imaging (MRI) T2 mapping. It wa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Journal of Experimental Orthopaedics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40634-021-00413-3 |
| _version_ | 1827356154356826112 |
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| author | Ken Iida Yusuke Hashimoto Yohei Nishida Shinya Yamasaki Hiroaki Nakamura |
| author_facet | Ken Iida Yusuke Hashimoto Yohei Nishida Shinya Yamasaki Hiroaki Nakamura |
| author_sort | Ken Iida |
| collection | DOAJ |
| description | Abstract Purpose This study evaluated the regenerated cartilage after opening‐wedge high tibial osteotomy (OWHTO) with concomitant microfracture by second‐look arthroscopy, Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score and magnetic resonance imaging (MRI) T2 mapping. It was hypothesised that cartilage regeneration can be achieved by HTO, but the quality of regenerated cartilage is not normal cartilage. Methods OWHTO was performed in eight knees of seven patients (mean age, 57.6 ± 5.2 years). Microfracture for the cartilage defect was performed followed by OWHTO, and second‐look arthroscopy was performed at the time of plate removal (14.1 ± 4.5 months after OWHTO). MRI was assessed at three months and one year after surgery. The status of articular cartilage regeneration was assessed by the ICRS grade, MOCART score and T2 value. Results The number of subjects in ICRS grade 1/2/3/4 changed significantly from 0/0/4/4 preoperatively to 0/2/6/0 postoperatively in the medial femoral condyle (MFC) (P < 0.05) and 0/0/0/8 preoperatively to 0/0/7/1 postoperatively in the medial tibial plateau (MTP) (P < 0.05). Mean MOCART scores for MFC and MTP at one year after surgery exhibited significant increases compared with the results at three months after surgery. Mean T2 values for MFC and MTP did not differ at three months and one year after surgery. Conclusion The appearance and morphological evaluation by ICRS grade and MOCART score of regenerated cartilage were improved after OWHTO with concomitant microfracture. However, there were no significant qualitative differences in T2 values. This suggests that the regenerated cartilage tissue was likely to be insufficient cartilage. Level of evidence Level IV, therapeutic case series. |
| first_indexed | 2024-03-08T04:55:42Z |
| format | Article |
| id | doaj.art-a6b07a38c05d4221928bd4a45837dc01 |
| institution | Directory Open Access Journal |
| issn | 2197-1153 |
| language | English |
| last_indexed | 2024-03-08T04:55:42Z |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Experimental Orthopaedics |
| spelling | doaj.art-a6b07a38c05d4221928bd4a45837dc012024-02-07T15:16:42ZengWileyJournal of Experimental Orthopaedics2197-11532021-01-0181n/an/a10.1186/s40634-021-00413-3Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary studyKen Iida0Yusuke Hashimoto1Yohei Nishida2Shinya Yamasaki3Hiroaki Nakamura4Department of Orthopaedic SurgeryOsaka City University Graduate School of MedicineOsakaJapanDepartment of Orthopaedic SurgeryOsaka City University Graduate School of MedicineOsakaJapanDepartment of Orthopaedic SurgeryOsaka City University Graduate School of MedicineOsakaJapanDepartment of Orthopaedic SurgeryOsaka City General HospitalOsakaJapanDepartment of Orthopaedic SurgeryOsaka City University Graduate School of MedicineOsakaJapanAbstract Purpose This study evaluated the regenerated cartilage after opening‐wedge high tibial osteotomy (OWHTO) with concomitant microfracture by second‐look arthroscopy, Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score and magnetic resonance imaging (MRI) T2 mapping. It was hypothesised that cartilage regeneration can be achieved by HTO, but the quality of regenerated cartilage is not normal cartilage. Methods OWHTO was performed in eight knees of seven patients (mean age, 57.6 ± 5.2 years). Microfracture for the cartilage defect was performed followed by OWHTO, and second‐look arthroscopy was performed at the time of plate removal (14.1 ± 4.5 months after OWHTO). MRI was assessed at three months and one year after surgery. The status of articular cartilage regeneration was assessed by the ICRS grade, MOCART score and T2 value. Results The number of subjects in ICRS grade 1/2/3/4 changed significantly from 0/0/4/4 preoperatively to 0/2/6/0 postoperatively in the medial femoral condyle (MFC) (P < 0.05) and 0/0/0/8 preoperatively to 0/0/7/1 postoperatively in the medial tibial plateau (MTP) (P < 0.05). Mean MOCART scores for MFC and MTP at one year after surgery exhibited significant increases compared with the results at three months after surgery. Mean T2 values for MFC and MTP did not differ at three months and one year after surgery. Conclusion The appearance and morphological evaluation by ICRS grade and MOCART score of regenerated cartilage were improved after OWHTO with concomitant microfracture. However, there were no significant qualitative differences in T2 values. This suggests that the regenerated cartilage tissue was likely to be insufficient cartilage. Level of evidence Level IV, therapeutic case series.https://doi.org/10.1186/s40634-021-00413-3High tibial osteotomyOpening wedgeKneeCartilage regenerationT2 mapping |
| spellingShingle | Ken Iida Yusuke Hashimoto Yohei Nishida Shinya Yamasaki Hiroaki Nakamura Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study Journal of Experimental Orthopaedics High tibial osteotomy Opening wedge Knee Cartilage regeneration T2 mapping |
| title | Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study |
| title_full | Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study |
| title_fullStr | Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study |
| title_full_unstemmed | Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study |
| title_short | Evaluation of regenerated cartilage using T2 mapping methods after opening‐wedge high tibial osteotomy with microfracture at the cartilage defect: a preliminary study |
| title_sort | evaluation of regenerated cartilage using t2 mapping methods after opening wedge high tibial osteotomy with microfracture at the cartilage defect a preliminary study |
| topic | High tibial osteotomy Opening wedge Knee Cartilage regeneration T2 mapping |
| url | https://doi.org/10.1186/s40634-021-00413-3 |
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