Effect of Deep Eutectic System (DES) on Oral Bioavailability of Celecoxib: In Silico, In Vitro, and In Vivo Study

Effect of Deep Eutectic System (DES) on Oral Bioavailability of Celecoxib: In Silico, In Vitro, and In Vivo Study

Different deep eutectic systems (DES) of choline chloride (CC)–urea (UA) (1:2), CC–glycerol (GLY) (1:2), CC–malonic acid (MA) (1:1), and CC–ascorbic acid (AA) (2:1) were generated and characterized by polarized light microscope (PLM) and Fourier transform infrared spectroscope (FTIR). The equilibriu...

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Bibliographic Details
Main Authors: Soumalya Chakraborty, Rohit Y. Sathe, Jaydeep H. Chormale, Ashish Dangi, Prasad V. Bharatam, Arvind K. Bansal
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
deep eutectic system
poorly soluble drugs
celecoxib
solubility
dissolution
oral bioavailability
Online Access:https://www.mdpi.com/1999-4923/15/9/2351

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