Oxycodone in mastectomy surgery

The pharmacological effects of oxycodone and morphine are close. The analgesic potency between oxycodone and morphine is presumed to have a 1:1 ratio. Fentanyl-to-morphine ratio was 1:100. The plasma levels of oxycodone are more active than morphine. The analgesic potency of oxycodone is about 30% g...

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Main Authors: Putu Pramana Suarjaya, Cynthia Dewi Sinardja, Aninda Tanggono
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Bali Journal of Anesthesiology
Subjects:
Online Access:http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=72;epage=74;aulast=Suarjaya
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author Putu Pramana Suarjaya
Cynthia Dewi Sinardja
Aninda Tanggono
author_facet Putu Pramana Suarjaya
Cynthia Dewi Sinardja
Aninda Tanggono
author_sort Putu Pramana Suarjaya
collection DOAJ
description The pharmacological effects of oxycodone and morphine are close. The analgesic potency between oxycodone and morphine is presumed to have a 1:1 ratio. Fentanyl-to-morphine ratio was 1:100. The plasma levels of oxycodone are more active than morphine. The analgesic potency of oxycodone is about 30% greater than that of morphine and slightly longer acting than morphine. Oxycodone showed a longer duration of action and a better analgesic effect than fentanyl. Oxycodone could minimize patient hemodynamic responses to sudden stimuli such as endotracheal intubation, similar to fentanyl. A 41-year-old woman admitted to the hospital with elective surgery of mastectomy surgery. There was no complaint about the lump in mammae dextra. For the surgery, induction bolus of oxycodone 0.2 mg/kg was diluted with normal saline; for endotracheal intubation and postoperative, we used oxycodone with patient-controlled analgesia. Hemodynamic curves were within the normal limits, she had no complaints of postoperative nausea and vomiting or pruritus, and she was discharged on the 3rd day.
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spelling doaj.art-a6b2020cc35f424586f229177962e66d2022-12-21T18:52:25ZengWolters Kluwer Medknow PublicationsBali Journal of Anesthesiology2549-22762020-01-0142727410.4103/BJOA.BJOA_16_19Oxycodone in mastectomy surgeryPutu Pramana SuarjayaCynthia Dewi SinardjaAninda TanggonoThe pharmacological effects of oxycodone and morphine are close. The analgesic potency between oxycodone and morphine is presumed to have a 1:1 ratio. Fentanyl-to-morphine ratio was 1:100. The plasma levels of oxycodone are more active than morphine. The analgesic potency of oxycodone is about 30% greater than that of morphine and slightly longer acting than morphine. Oxycodone showed a longer duration of action and a better analgesic effect than fentanyl. Oxycodone could minimize patient hemodynamic responses to sudden stimuli such as endotracheal intubation, similar to fentanyl. A 41-year-old woman admitted to the hospital with elective surgery of mastectomy surgery. There was no complaint about the lump in mammae dextra. For the surgery, induction bolus of oxycodone 0.2 mg/kg was diluted with normal saline; for endotracheal intubation and postoperative, we used oxycodone with patient-controlled analgesia. Hemodynamic curves were within the normal limits, she had no complaints of postoperative nausea and vomiting or pruritus, and she was discharged on the 3rd day.http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=72;epage=74;aulast=Suarjayafentanylhemodynamicmastectomy surgerymorphineoxycodone
spellingShingle Putu Pramana Suarjaya
Cynthia Dewi Sinardja
Aninda Tanggono
Oxycodone in mastectomy surgery
Bali Journal of Anesthesiology
fentanyl
hemodynamic
mastectomy surgery
morphine
oxycodone
title Oxycodone in mastectomy surgery
title_full Oxycodone in mastectomy surgery
title_fullStr Oxycodone in mastectomy surgery
title_full_unstemmed Oxycodone in mastectomy surgery
title_short Oxycodone in mastectomy surgery
title_sort oxycodone in mastectomy surgery
topic fentanyl
hemodynamic
mastectomy surgery
morphine
oxycodone
url http://www.bjoaonline.com/article.asp?issn=2549-2276;year=2020;volume=4;issue=2;spage=72;epage=74;aulast=Suarjaya
work_keys_str_mv AT putupramanasuarjaya oxycodoneinmastectomysurgery
AT cynthiadewisinardja oxycodoneinmastectomysurgery
AT anindatanggono oxycodoneinmastectomysurgery