Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model

Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medications for the treatment of mood disorders. Yet, individual response to SSRIs is highly variable, with only a portion of patients showing the desired therapeutic effect. To better understand the molecular basis und...

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Bibliographic Details
Main Authors:	Maja Kesić, Gordana Mokrović, Ante Tvrdeić, Branko Miše, Jasminka Štefulj, Lipa Čičin-Šain
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Psychiatry
Subjects:	5-HT serotonin transporter animal model SSRI anxiety depression
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2021.741222/full

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