Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction
Background: Subjective diagnostic test of food allergy is hugely biased, resulting in irrational diet avoidance. Additional objective tools by skin prick test following food provocation test resulting more accurate cause and prevalence on population. Purpose: To evaluate the compatibility of clinica...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Indonesian |
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Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga
2017-08-01
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| Series: | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/BIKK/article/view/5560 |
| _version_ | 1827673674821402624 |
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| author | Azwin Lubis Wisnu Barlianto Anang Endaryanto Ariyanto Harsono |
| author_facet | Azwin Lubis Wisnu Barlianto Anang Endaryanto Ariyanto Harsono |
| author_sort | Azwin Lubis |
| collection | DOAJ |
| description | Background: Subjective diagnostic test of food allergy is hugely biased, resulting in irrational diet avoidance. Additional objective tools by skin prick test following food provocation test resulting more accurate cause and prevalence on population. Purpose: To evaluate the compatibility of clinical symptoms with skin prick test and provocation test for imunoglobulin E (IgE) mediated food allergy in Dr. Soetomo Hospital Surabaya. Methods: Cross sectional observational analytic study. Patient with allergy symptoms, diagnosed with food skin prick test followed by food provocation test. McNemar test and Kappa were used to analyze compatibility of skin prick test with food provocation test. Sensitivity and spesificity test of skin prick test toward food provocation test were done. Results: McNemar test between skin prick test and food provocation test are valued p<0.05 in all food allergen, except fruit p=0.607, but all Kappa test are low p<0.6. Fruit and chocolate showed low sensitivity (0.307;0.409) but with high spesificity (0.823;0.8333); egg and shrimp showed high sensitivity (0.777;1.000) but low spesificity (0.548;0.352); cow’s milk, seafish, and chicken meat showed sensitivity (0.636;1.000;0.785) and high specifity (0.607;0.625;0.631); fresh water fish showed low sensitivity and spesificity (0.500;0.583). IgE mediated symptoms profile is dominated by cough except for shrimp, and non-IgE mediated also is dominated by cough except seafish and shrimp. Conclusion: There is incompatibilty between result of skin prick test and food provocation test in IgE mediated food allergy. IgE mediated and non-mediated food allergy symptoms are dominated by airway, gastrointestinal tract, and skin symptoms. Food allergy symptoms are more related to IgE mediated than non-IgE mediated. |
| first_indexed | 2024-03-10T04:28:01Z |
| format | Article |
| id | doaj.art-a6b3d9d15e3c4e9690aff7b7cff6f99e |
| institution | Directory Open Access Journal |
| issn | 1978-4279 2549-4082 |
| language | Indonesian |
| last_indexed | 2024-03-10T04:28:01Z |
| publishDate | 2017-08-01 |
| publisher | Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga |
| record_format | Article |
| series | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| spelling | doaj.art-a6b3d9d15e3c4e9690aff7b7cff6f99e2023-11-23T06:27:43ZindDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas AirlanggaBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)1978-42792549-40822017-08-0129210611610.20473/bikk.V29.2.2017.106-1164383Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross ReactionAzwin Lubis0Wisnu Barlianto1Anang Endaryanto2Ariyanto Harsono3Departemen Ilmu Kesehatan Anak Fakultas Kedokteran, Universitas Airlangga Rumah Sakit Dr. Soetomo SurabayaDepartemen Ilmu Kesehatan Anak Fakultas Kedokteran, Universitas Brawijaya Rumah Sakit Saiful Anwar MalangDepartemen Ilmu Kesehatan Anak Fakultas Kedokteran, Universitas Airlangga Rumah Sakit Dr. Soetomo SurabayaDepartemen Ilmu Kesehatan Anak Fakultas Kedokteran, Universitas Airlangga Rumah Sakit Dr. Soetomo SurabayaBackground: Subjective diagnostic test of food allergy is hugely biased, resulting in irrational diet avoidance. Additional objective tools by skin prick test following food provocation test resulting more accurate cause and prevalence on population. Purpose: To evaluate the compatibility of clinical symptoms with skin prick test and provocation test for imunoglobulin E (IgE) mediated food allergy in Dr. Soetomo Hospital Surabaya. Methods: Cross sectional observational analytic study. Patient with allergy symptoms, diagnosed with food skin prick test followed by food provocation test. McNemar test and Kappa were used to analyze compatibility of skin prick test with food provocation test. Sensitivity and spesificity test of skin prick test toward food provocation test were done. Results: McNemar test between skin prick test and food provocation test are valued p<0.05 in all food allergen, except fruit p=0.607, but all Kappa test are low p<0.6. Fruit and chocolate showed low sensitivity (0.307;0.409) but with high spesificity (0.823;0.8333); egg and shrimp showed high sensitivity (0.777;1.000) but low spesificity (0.548;0.352); cow’s milk, seafish, and chicken meat showed sensitivity (0.636;1.000;0.785) and high specifity (0.607;0.625;0.631); fresh water fish showed low sensitivity and spesificity (0.500;0.583). IgE mediated symptoms profile is dominated by cough except for shrimp, and non-IgE mediated also is dominated by cough except seafish and shrimp. Conclusion: There is incompatibilty between result of skin prick test and food provocation test in IgE mediated food allergy. IgE mediated and non-mediated food allergy symptoms are dominated by airway, gastrointestinal tract, and skin symptoms. Food allergy symptoms are more related to IgE mediated than non-IgE mediated.https://e-journal.unair.ac.id/BIKK/article/view/5560allergy symptomsskin prick testfood provocation testcompatibilitysensitivityspesificitysymptoms profile |
| spellingShingle | Azwin Lubis Wisnu Barlianto Anang Endaryanto Ariyanto Harsono Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) allergy symptoms skin prick test food provocation test compatibility sensitivity spesificity symptoms profile |
| title | Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction |
| title_full | Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction |
| title_fullStr | Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction |
| title_full_unstemmed | Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction |
| title_short | Compatibility of Clinical Manifestation with Skin Prick Test Result and Food Provocation Test in Food Cross Reaction |
| title_sort | compatibility of clinical manifestation with skin prick test result and food provocation test in food cross reaction |
| topic | allergy symptoms skin prick test food provocation test compatibility sensitivity spesificity symptoms profile |
| url | https://e-journal.unair.ac.id/BIKK/article/view/5560 |
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