VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity

VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity

Voltage-Dependent Anion-selective Channel isoform 1 (VDAC1) is the most abundant isoform of the outer mitochondrial membrane (OMM) porins and the principal gate for ions and metabolites to and from the organelle. VDAC1 is also involved in a number of additional functions, such as the regulation of a...

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Bibliographic Details
Main Authors:	Andrea Magrì, Salvatore Antonio Maria Cubisino, Giuseppe Battiato, Cristiana Lucia Rita Lipari, Stefano Conti Nibali, Miriam Wissam Saab, Alessandra Pittalà, Angela Maria Amorini, Vito De Pinto, Angela Messina
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	International Journal of Molecular Sciences
Subjects:	mitochondria VDAC1 knockout HAP1 cells complex I respiratory reserve(s)
Online Access:	https://www.mdpi.com/1422-0067/24/4/3687

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