Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway

Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway

<p>Abstract</p> <p>Background</p> <p>The lack of effective treatments for gliomas makes them a significant health problem and highlights the need for the development of novel and innovative treatment approaches. Immunotherapy is an appealing strategy because of the pote...

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Bibliographic Details
Main Authors: Konkankit Veerauo V, Kim Won, Koya Richard C, Eskin Ascia, Dam Mai-Anh, Nelson Stanley, Ribas Antoni, Liau Linda M, Prins Robert M
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Journal of Translational Medicine
Subjects:
T cells
tumor immunity
decitabine
cancer testis antigens
Fas/Fas Ligand
Online Access:http://www.translational-medicine.com/content/9/1/192

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