Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats
<p>Purpose: to determine the quantitative patterns and gradations of the degree of manifestation of changes in IRT indicators, depending on LDF data, corresponding to different conditions and peripheral blood flow disorders in the skin of laboratory rats. Material and Methods. Microcirculation...
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| Format: | Article |
| Language: | Russian |
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Saratov State Medical University
2017-12-01
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| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2017_04-1_901-907.pdf |
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| author | Datsenko A.V. Fomina T.V. Dyoshin I.A. Kazmin V.I. |
| author_facet | Datsenko A.V. Fomina T.V. Dyoshin I.A. Kazmin V.I. |
| author_sort | Datsenko A.V. |
| collection | DOAJ |
| description | <p>Purpose: to determine the quantitative patterns and gradations of the degree of manifestation of changes in IRT indicators, depending on LDF data, corresponding to different conditions and peripheral blood flow disorders in the skin of laboratory rats. Material and Methods. Microcirculation of blood in bio-objects in background studies and immediately after the experimental modeling of hypobaric hypoxia was determined with the help of LDF, while simultaneously performing remote dynamic infrared thermography of the rats'tail skin. A comparison of LDF and IRT data was carried out using statistical methods of correlation-regression analysis. Results. The decrease in tissue blood flow was accompanied by a decrease in temperature, with an increase in perfusion of blood along the microcirculation pathways, the temperature of the skin surface increased. The quantitative criteria of experimental diagnostics in the form of boundary values and ranges of temperature indicators for an estimation of a different degree of severity of violations of the microcirculation of blood (peripheral hemodynamics) are determined. With a decrease or increase in tissue blood flow to 10, 10-25, 25-40 and more than 40% of the baseline (background control), the negative or positive skin surface temperature increase was up to 0.6, 0.6-1.2, 1.2-1.8 and more than 1.8°C respectively. Conclusion. Results of thermal imaging can be used as a criterion for predictive assessment of the state and changes in cutaneous peripheral blood flow in laboratory rats.</p> |
| first_indexed | 2024-12-18T23:43:46Z |
| format | Article |
| id | doaj.art-a6bd4b1d23de4cb9aacba513629c164e |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-18T23:43:46Z |
| publishDate | 2017-12-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-a6bd4b1d23de4cb9aacba513629c164e2022-12-21T20:47:17ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182017-12-011349019074911Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory ratsDatsenko A.V.0Fomina T.V.1Dyoshin I.A.2Kazmin V.I.3State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological AgencyState Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological AgencyState Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological AgencyState Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency<p>Purpose: to determine the quantitative patterns and gradations of the degree of manifestation of changes in IRT indicators, depending on LDF data, corresponding to different conditions and peripheral blood flow disorders in the skin of laboratory rats. Material and Methods. Microcirculation of blood in bio-objects in background studies and immediately after the experimental modeling of hypobaric hypoxia was determined with the help of LDF, while simultaneously performing remote dynamic infrared thermography of the rats'tail skin. A comparison of LDF and IRT data was carried out using statistical methods of correlation-regression analysis. Results. The decrease in tissue blood flow was accompanied by a decrease in temperature, with an increase in perfusion of blood along the microcirculation pathways, the temperature of the skin surface increased. The quantitative criteria of experimental diagnostics in the form of boundary values and ranges of temperature indicators for an estimation of a different degree of severity of violations of the microcirculation of blood (peripheral hemodynamics) are determined. With a decrease or increase in tissue blood flow to 10, 10-25, 25-40 and more than 40% of the baseline (background control), the negative or positive skin surface temperature increase was up to 0.6, 0.6-1.2, 1.2-1.8 and more than 1.8°C respectively. Conclusion. Results of thermal imaging can be used as a criterion for predictive assessment of the state and changes in cutaneous peripheral blood flow in laboratory rats.</p>http://www.ssmj.ru/system/files/2017_04-1_901-907.pdfinfrared thermographylaser Doppler floumetrymicrocirculation of bloodthermovision |
| spellingShingle | Datsenko A.V. Fomina T.V. Dyoshin I.A. Kazmin V.I. Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats Саратовский научно-медицинский журнал infrared thermography laser Doppler floumetry microcirculation of blood thermovision |
| title | Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| title_full | Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| title_fullStr | Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| title_full_unstemmed | Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| title_short | Investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| title_sort | investigation of the relationship between changes in thermographic and flowmetric parameters of skin peripheral hemodynamics in laboratory rats |
| topic | infrared thermography laser Doppler floumetry microcirculation of blood thermovision |
| url | http://www.ssmj.ru/system/files/2017_04-1_901-907.pdf |
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