Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature
Background: In the medical field, it is increasingly common to observe the use of nanotubes, for example, in the administration of drugs. However, nanotubes raise concerns for male fertility due to potential effects on hormone levels and sperm quality observed in animal studies. In addition, animal...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2024-03-01
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| Series: | Archivio Italiano di Urologia e Andrologia |
| Subjects: | |
| Online Access: | https://www.pagepressjournals.org/index.php/aiua/article/view/12192 |
| _version_ | 1797269198224752640 |
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| author | William Felipe Fernández Zapata Yamile Cardona Maya Cesar Isaza Merino Walter D. Cardona Maya |
| author_facet | William Felipe Fernández Zapata Yamile Cardona Maya Cesar Isaza Merino Walter D. Cardona Maya |
| author_sort | William Felipe Fernández Zapata |
| collection | DOAJ |
| description |
Background: In the medical field, it is increasingly common to observe the use of nanotubes, for example, in the administration of drugs. However, nanotubes raise concerns for male fertility due to potential effects on hormone levels and sperm quality observed in animal studies. In addition, animal exposure to multi-walled carbon nanotube models found alterations in hormone levels, sperm motility, and sperm count. Limited evidence in humans suggests no adverse effects, but further research is needed. This study aimed to perform a systematic review to assess the in vitro effects of nanotubes on semen and fertility in humans. Methods: We included all published in vitro studies about semen or sperm or male fertility and nanotubes in humans. A search was conducted in LILACS, PubMed, and SCOPUS as of May 2023. The risk of bias was assessed using the QUIN tool. Results: Four studies using nanotubes on human sperm were included, nanotubes exposure appears not to affect sperm viability; however, some alterations to motility, velocity and production of reactive oxygen species were reported. Limited evidence is provided because of the small quantity of publications. Conclusions: Nanotubes appear to have no adverse effects on human sperm.
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| first_indexed | 2024-04-25T01:44:33Z |
| format | Article |
| id | doaj.art-a6c1b643de304e53a42e2cc3db39f911 |
| institution | Directory Open Access Journal |
| issn | 1124-3562 2282-4197 |
| language | English |
| last_indexed | 2024-04-25T01:44:33Z |
| publishDate | 2024-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Archivio Italiano di Urologia e Andrologia |
| spelling | doaj.art-a6c1b643de304e53a42e2cc3db39f9112024-03-07T23:11:56ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972024-03-0110.4081/aiua.2024.12192Effects of nanotubes on semen quality and fertility in humans: a systematic review of literatureWilliam Felipe Fernández Zapata0Yamile Cardona Maya1Cesar Isaza Merino2Walter D. Cardona Maya3“SYMBIOSIS” Research Hotbed in Human Reproduction and Gestation, Faculty of Medicine, University of Antioquia, UdeA, Medellín; Reproduction Group, Department of Microbiology and Parasitology, Faculty of Medicine, University of Antioquia, UdeA, MedellínDepartment of Basic Foundation, Pascual Bravo University Institution, MedellínDepartment of Mechanical Engineering, Faculty of Engineering, University of Antioquia, UdeA, MedellínReproduction Group, Department of Microbiology and Parasitology, Faculty of Medicine, University of Antioquia, UdeA, Medellín Background: In the medical field, it is increasingly common to observe the use of nanotubes, for example, in the administration of drugs. However, nanotubes raise concerns for male fertility due to potential effects on hormone levels and sperm quality observed in animal studies. In addition, animal exposure to multi-walled carbon nanotube models found alterations in hormone levels, sperm motility, and sperm count. Limited evidence in humans suggests no adverse effects, but further research is needed. This study aimed to perform a systematic review to assess the in vitro effects of nanotubes on semen and fertility in humans. Methods: We included all published in vitro studies about semen or sperm or male fertility and nanotubes in humans. A search was conducted in LILACS, PubMed, and SCOPUS as of May 2023. The risk of bias was assessed using the QUIN tool. Results: Four studies using nanotubes on human sperm were included, nanotubes exposure appears not to affect sperm viability; however, some alterations to motility, velocity and production of reactive oxygen species were reported. Limited evidence is provided because of the small quantity of publications. Conclusions: Nanotubes appear to have no adverse effects on human sperm. https://www.pagepressjournals.org/index.php/aiua/article/view/12192Nanotubessemenfertilitynanoparticlesreproduction |
| spellingShingle | William Felipe Fernández Zapata Yamile Cardona Maya Cesar Isaza Merino Walter D. Cardona Maya Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature Archivio Italiano di Urologia e Andrologia Nanotubes semen fertility nanoparticles reproduction |
| title | Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature |
| title_full | Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature |
| title_fullStr | Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature |
| title_full_unstemmed | Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature |
| title_short | Effects of nanotubes on semen quality and fertility in humans: a systematic review of literature |
| title_sort | effects of nanotubes on semen quality and fertility in humans a systematic review of literature |
| topic | Nanotubes semen fertility nanoparticles reproduction |
| url | https://www.pagepressjournals.org/index.php/aiua/article/view/12192 |
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