Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells

Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells

BackgroundThere is increasing evidence that adipocytes play an active role in the cancer microenvironment. We have previously reported that adipocytes interact with acute lymphoblastic leukemia (ALL) cells, contributing to chemotherapy resistance and treatment failure. In the present study, we inves...

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Bibliographic Details
Main Authors: Jonathan Tucci, Ting Chen, Katherine Margulis, Etan Orgel, Rebecca L. Paszkiewicz, Michael D. Cohen, Matthew J. Oberley, Rachel Wahhab, Anthony E. Jones, Ajit S. Divakaruni, Cheng-Chih Hsu, Sarah E. Noll, Xia Sheng, Richard N. Zare, Steven D. Mittelman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
adipocytes
FFA
microenvironment
leukemia
lipid droplets
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.665763/full

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