Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves
<abstract language="eng">Iron is a vital element in the human metabolism. It plays a central role in erythropoiesis and is also involved in many other intracellular processes in all the tissues of the body. Blood donation results in a substantial (200 to 250 ng) loss of iron at each...
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| Format: | Article |
| Language: | English |
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Elsevier
2008-02-01
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000100015 |
| _version_ | 1818043143432437760 |
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| author | Rita C. Mousinho-Ribeiro Gabriella P. Sousa Thiago M. Nunes Marcelo C. Neves |
| author_facet | Rita C. Mousinho-Ribeiro Gabriella P. Sousa Thiago M. Nunes Marcelo C. Neves |
| author_sort | Rita C. Mousinho-Ribeiro |
| collection | DOAJ |
| description | <abstract language="eng">Iron is a vital element in the human metabolism. It plays a central role in erythropoiesis and is also involved in many other intracellular processes in all the tissues of the body. Blood donation results in a substantial (200 to 250 ng) loss of iron at each donation (425 to 475 ml) with subsequent mobilization of iron from body deposits. Repetitive donations of blood my cause the depletion of iron reserves in blood donors and thus cause health disorders. Recent reports have shown that iron reserves are generally small and iron depletion is more common in blood donors than in non-donors. The high frequency of iron deficiency in blood donors reported by these studies suggests a need for more accurate studies, as measurement of hemoglobin and hematicrit alone is insufficient to identify and exclude prospective blood donors with iron deficiency but without anemia. It is important, therefore, that blood banks evaluate the risk-benefit of implanting tests to analyze organism iron reserves such as the measurement of serum ferritin of all individuals who donate more than three times per year in order to make the blood donation process safer for both donors and transfused patients. |
| first_indexed | 2024-12-10T08:57:31Z |
| format | Article |
| id | doaj.art-a6c5517570074b75ab345026aa4ceffd |
| institution | Directory Open Access Journal |
| issn | 1516-8484 1806-0870 |
| language | English |
| last_indexed | 2024-12-10T08:57:31Z |
| publishDate | 2008-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Brasileira de Hematologia e Hemoterapia |
| spelling | doaj.art-a6c5517570074b75ab345026aa4ceffd2022-12-22T01:55:22ZengElsevierRevista Brasileira de Hematologia e Hemoterapia1516-84841806-08702008-02-01301626410.1590/S1516-84842008000100015Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reservesRita C. Mousinho-RibeiroGabriella P. SousaThiago M. NunesMarcelo C. Neves<abstract language="eng">Iron is a vital element in the human metabolism. It plays a central role in erythropoiesis and is also involved in many other intracellular processes in all the tissues of the body. Blood donation results in a substantial (200 to 250 ng) loss of iron at each donation (425 to 475 ml) with subsequent mobilization of iron from body deposits. Repetitive donations of blood my cause the depletion of iron reserves in blood donors and thus cause health disorders. Recent reports have shown that iron reserves are generally small and iron depletion is more common in blood donors than in non-donors. The high frequency of iron deficiency in blood donors reported by these studies suggests a need for more accurate studies, as measurement of hemoglobin and hematicrit alone is insufficient to identify and exclude prospective blood donors with iron deficiency but without anemia. It is important, therefore, that blood banks evaluate the risk-benefit of implanting tests to analyze organism iron reserves such as the measurement of serum ferritin of all individuals who donate more than three times per year in order to make the blood donation process safer for both donors and transfused patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000100015Iron reservesblood donationserum ferritin |
| spellingShingle | Rita C. Mousinho-Ribeiro Gabriella P. Sousa Thiago M. Nunes Marcelo C. Neves Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves Revista Brasileira de Hematologia e Hemoterapia Iron reserves blood donation serum ferritin |
| title | Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves |
| title_full | Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves |
| title_fullStr | Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves |
| title_full_unstemmed | Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves |
| title_short | Impacto da doação de sangue nos depósitos de ferro do organismo de doadores Impact of blood donation on donor iron reserves |
| title_sort | impacto da doacao de sangue nos depositos de ferro do organismo de doadores impact of blood donation on donor iron reserves |
| topic | Iron reserves blood donation serum ferritin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000100015 |
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