Antigen Design for Successful Isolation of Highly Challenging Therapeutic Anti-GPCR Antibodies
G-protein-coupled receptors (GPCR) transmit extracellular signals into cells to regulate a variety of cellular functions and are closely related to the homeostasis of the human body and the progression of various types of diseases. Great attention has been paid to GPCRs as excellent drug targets, an...
Main Authors: | Man-Seok Ju, Sang Taek Jung |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/21/8240 |
Similar Items
-
Rapid identification of highly potent human anti-GPCR antagonist monoclonal antibodies
by: Martin J. Scott, et al.
Published: (2020-01-01) -
Probing GPCR Dimerization Using Peptides
by: Zara Farooq, et al.
Published: (2022-07-01) -
Conformational dynamics in GPCR signaling by NMR
by: Yunfei Hu, et al.
Published: (2022-08-01) -
The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)
by: M. Claire Cato, et al.
Published: (2021-03-01) -
Class-Switching of B Lymphocytes by DNA and Cell Immunization for Stereospecific Monoclonal Antibodies against Native GPCR
by: Yushi Isozaki, et al.
Published: (2021-11-01)