Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality

Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease characterized by a severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages. Herein, we report a 58-year-old male who had Chlamydia pneumoniae-related pneumonia, followed by aggr...

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Main Authors: Zheng-Yi Huang, Tzong-Shi Chieuh, Kwei-Shuai Hwang, Tzu-Chuan Huang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=3;spage=392;epage=394;aulast=Huang
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author Zheng-Yi Huang
Tzong-Shi Chieuh
Kwei-Shuai Hwang
Tzu-Chuan Huang
author_facet Zheng-Yi Huang
Tzong-Shi Chieuh
Kwei-Shuai Hwang
Tzu-Chuan Huang
author_sort Zheng-Yi Huang
collection DOAJ
description Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease characterized by a severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages. Herein, we report a 58-year-old male who had Chlamydia pneumoniae-related pneumonia, followed by aggressive HLH. An abnormal cytogenetic profile was also detected. To our knowledge, this is the first report of an adult patient with C. pneumonia-associated HLH.
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spelling doaj.art-a6cf5d57af09407dae5752f03652c0902022-12-22T00:53:45ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292015-01-0158339239410.4103/0377-4929.162928Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormalityZheng-Yi HuangTzong-Shi ChieuhKwei-Shuai HwangTzu-Chuan HuangHemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease characterized by a severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages. Herein, we report a 58-year-old male who had Chlamydia pneumoniae-related pneumonia, followed by aggressive HLH. An abnormal cytogenetic profile was also detected. To our knowledge, this is the first report of an adult patient with C. pneumonia-associated HLH.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=3;spage=392;epage=394;aulast=HuangChlamydia pneumoniae hemophagocytic lymphohistiocytosiskaryotype
spellingShingle Zheng-Yi Huang
Tzong-Shi Chieuh
Kwei-Shuai Hwang
Tzu-Chuan Huang
Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
Indian Journal of Pathology and Microbiology
Chlamydia pneumoniae
hemophagocytic lymphohistiocytosis
karyotype
title Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
title_full Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
title_fullStr Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
title_full_unstemmed Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
title_short Chlamydia pneumoniae-related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
title_sort chlamydia pneumoniae related hemophagocytic lymphohistiocytosis in an adult patient with clonal karyotype abnormality
topic Chlamydia pneumoniae
hemophagocytic lymphohistiocytosis
karyotype
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2015;volume=58;issue=3;spage=392;epage=394;aulast=Huang
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AT tzongshichieuh chlamydiapneumoniaerelatedhemophagocyticlymphohistiocytosisinanadultpatientwithclonalkaryotypeabnormality
AT kweishuaihwang chlamydiapneumoniaerelatedhemophagocyticlymphohistiocytosisinanadultpatientwithclonalkaryotypeabnormality
AT tzuchuanhuang chlamydiapneumoniaerelatedhemophagocyticlymphohistiocytosisinanadultpatientwithclonalkaryotypeabnormality