Vitamin D deficiency in critically ill children

Background:In critical illness, there also is evidence of rapid falls in circulating 25(OH)D concentrations. So, we aim to assess the prevalence of VDD in a pediatric ICU (PICU) patients and to determine whether there is any relationship between VDD and illness severity and mortality. Patients and m...

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Main Authors: Eman Abo EL Magd M. Ibrahim*, Ahmed El-Abd Ahmad, Mohammed H. Hassan
Format: Article
Language:English
Published: South Valley University, Faculty of Medicine 2020-07-01
Series:SVU - International Journal of Medical Sciences
Subjects:
Online Access:https://svuijm.journals.ekb.eg/article_111893.html
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author Eman Abo EL Magd M. Ibrahim*
Ahmed El-Abd Ahmad
Mohammed H. Hassan
author_facet Eman Abo EL Magd M. Ibrahim*
Ahmed El-Abd Ahmad
Mohammed H. Hassan
author_sort Eman Abo EL Magd M. Ibrahim*
collection DOAJ
description Background:In critical illness, there also is evidence of rapid falls in circulating 25(OH)D concentrations. So, we aim to assess the prevalence of VDD in a pediatric ICU (PICU) patients and to determine whether there is any relationship between VDD and illness severity and mortality. Patients and methods:this is a case control study that included 40 children :20 patient admitted to pediatric intensive care unit in Qena university at time of the study(from January 2018 till December 2018) compared to 20 apparently healthy well-matched children regarding age and sex to be compared as controls.All patients subjected to: Full history,detailed physical examination,diagnostic modalities as: laboratory investigation and severity of illness was assessed with the pediatric risk of mortality III Result: Our study included 40 child with the age of patientsrangedfrom5 monthsto12years withmean +/- SD 3.7 ±3 year. Male patients represented70%.In our study, the prevalence of vitamin D deficiency among critically ill children was 70 %we did not findsignificant correlation between 25(OH) vitamin D and pediatric risk of mortality III (PRISM III) Conclusion:Vitamin D Deficiency (VDD) prevalence was reported in 70% of the critically ill patients, and it was observed to be related to multiple organ dysfunctions and rapid clinicaldeterioration.
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spelling doaj.art-a6d023921be6437db97aab8d323d404f2022-12-22T01:42:24ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022020-07-01322025https://dx.doi.org/10.21608/svuijm.2020.111893 Vitamin D deficiency in critically ill childrenEman Abo EL Magd M. Ibrahim*0 Ahmed El-Abd Ahmad1Mohammed H. Hassan2https://orcid.org/0000-0003-2698-9438Pediatric Department, Qena Faculty of Medicine, South Valley UniversityPediatric Department, Qena Faculty of Medicine, South Valley UniversityDepartment of Medical Biochemistry and Molecular Biology, Qena Faculty of Medicine, South Valley UniBackground:In critical illness, there also is evidence of rapid falls in circulating 25(OH)D concentrations. So, we aim to assess the prevalence of VDD in a pediatric ICU (PICU) patients and to determine whether there is any relationship between VDD and illness severity and mortality. Patients and methods:this is a case control study that included 40 children :20 patient admitted to pediatric intensive care unit in Qena university at time of the study(from January 2018 till December 2018) compared to 20 apparently healthy well-matched children regarding age and sex to be compared as controls.All patients subjected to: Full history,detailed physical examination,diagnostic modalities as: laboratory investigation and severity of illness was assessed with the pediatric risk of mortality III Result: Our study included 40 child with the age of patientsrangedfrom5 monthsto12years withmean +/- SD 3.7 ±3 year. Male patients represented70%.In our study, the prevalence of vitamin D deficiency among critically ill children was 70 %we did not findsignificant correlation between 25(OH) vitamin D and pediatric risk of mortality III (PRISM III) Conclusion:Vitamin D Deficiency (VDD) prevalence was reported in 70% of the critically ill patients, and it was observed to be related to multiple organ dysfunctions and rapid clinicaldeterioration.https://svuijm.journals.ekb.eg/article_111893.htmlvitamin d deficiency; pediatric critical illness
spellingShingle Eman Abo EL Magd M. Ibrahim*
Ahmed El-Abd Ahmad
Mohammed H. Hassan
Vitamin D deficiency in critically ill children
SVU - International Journal of Medical Sciences
vitamin d deficiency; pediatric critical illness
title Vitamin D deficiency in critically ill children
title_full Vitamin D deficiency in critically ill children
title_fullStr Vitamin D deficiency in critically ill children
title_full_unstemmed Vitamin D deficiency in critically ill children
title_short Vitamin D deficiency in critically ill children
title_sort vitamin d deficiency in critically ill children
topic vitamin d deficiency; pediatric critical illness
url https://svuijm.journals.ekb.eg/article_111893.html
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AT ahmedelabdahmad vitaminddeficiencyincriticallyillchildren
AT mohammedhhassan vitaminddeficiencyincriticallyillchildren