Evaluation of homocysteine levels in neonatal calves with diarrhea

The aim of this study was to investigate the relationship between serum homocysteine (HCY), and creatinine, urea, venous blood gas and electrolytes values in neonatal calves with diarrhea. The study was conducted on a total of 30 calves, 20 with diarrhea and 10 healthy (control), with diarrhea compl...

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Main Authors: Süleyman KOZAT, Cumali ÖZKAN, Eda Nur OKMAN
Format: Article
Language:English
Published: Kafkas University, Faculty of Veterinary Medicine 2021-05-01
Series:Kafkas Universitesi Veteriner Fakültesi Dergisi
Subjects:
Online Access:https://vetdergikafkas.org/pdf.php?id=2805
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author Süleyman KOZAT
Cumali ÖZKAN
Eda Nur OKMAN
author_facet Süleyman KOZAT
Cumali ÖZKAN
Eda Nur OKMAN
author_sort Süleyman KOZAT
collection DOAJ
description The aim of this study was to investigate the relationship between serum homocysteine (HCY), and creatinine, urea, venous blood gas and electrolytes values in neonatal calves with diarrhea. The study was conducted on a total of 30 calves, 20 with diarrhea and 10 healthy (control), with diarrhea complaints, of diff erent races, sexes and ages ranging from 2-24 days. According to the venous blood gas results, the pCO2 and base deficit values of calves with diarrhea were significantly higher (P<0.001) compared to the control group values, while pH, pO2 and HCO3 values were significantly lower (P<0.001). While serum Na+ and Cl- concentrations in diarrheic calves did not show any statistical change when compared to the control group (P>0.05), serum K+ concentrations were statistically higher (P<0.001). Serum HCY, folate and vitamin B12 concentration values of diarrheic calves were significantly higher (P<0.001) when compared to the control group. As a result; in neonatal calves with diarrhea, it has been concluded that homocystein excretion is disrupted by low renal excretion due to decrease in glomerular filtration rate that caused hyperhomocysteine. In addition, it is thought that this study will shed light on studies that will reveal the eff ect of hyperhomocysteinemia in the cardiovascular system in diarrheic calves.
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spelling doaj.art-a6d1d8e739304f80ada00e5d9be626642023-06-19T06:29:55ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512021-05-0127327127710.9775/kvfd.2020.248942805Evaluation of homocysteine levels in neonatal calves with diarrheaSüleyman KOZAT0Cumali ÖZKAN1Eda Nur OKMAN2Department of Internal Medicine, Faculty of Veterinary Medicine, University of Yuzuncu Yil, TR-65080 Van - TURKEYDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Yuzuncu Yil, TR-65080 Van - TURKEYDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Yuzuncu Yil, TR-65080 Van - TURKEYThe aim of this study was to investigate the relationship between serum homocysteine (HCY), and creatinine, urea, venous blood gas and electrolytes values in neonatal calves with diarrhea. The study was conducted on a total of 30 calves, 20 with diarrhea and 10 healthy (control), with diarrhea complaints, of diff erent races, sexes and ages ranging from 2-24 days. According to the venous blood gas results, the pCO2 and base deficit values of calves with diarrhea were significantly higher (P<0.001) compared to the control group values, while pH, pO2 and HCO3 values were significantly lower (P<0.001). While serum Na+ and Cl- concentrations in diarrheic calves did not show any statistical change when compared to the control group (P>0.05), serum K+ concentrations were statistically higher (P<0.001). Serum HCY, folate and vitamin B12 concentration values of diarrheic calves were significantly higher (P<0.001) when compared to the control group. As a result; in neonatal calves with diarrhea, it has been concluded that homocystein excretion is disrupted by low renal excretion due to decrease in glomerular filtration rate that caused hyperhomocysteine. In addition, it is thought that this study will shed light on studies that will reveal the eff ect of hyperhomocysteinemia in the cardiovascular system in diarrheic calves.https://vetdergikafkas.org/pdf.php?id=2805homocysteineneonatal calfdiarrhea
spellingShingle Süleyman KOZAT
Cumali ÖZKAN
Eda Nur OKMAN
Evaluation of homocysteine levels in neonatal calves with diarrhea
Kafkas Universitesi Veteriner Fakültesi Dergisi
homocysteine
neonatal calf
diarrhea
title Evaluation of homocysteine levels in neonatal calves with diarrhea
title_full Evaluation of homocysteine levels in neonatal calves with diarrhea
title_fullStr Evaluation of homocysteine levels in neonatal calves with diarrhea
title_full_unstemmed Evaluation of homocysteine levels in neonatal calves with diarrhea
title_short Evaluation of homocysteine levels in neonatal calves with diarrhea
title_sort evaluation of homocysteine levels in neonatal calves with diarrhea
topic homocysteine
neonatal calf
diarrhea
url https://vetdergikafkas.org/pdf.php?id=2805
work_keys_str_mv AT suleymankozat evaluationofhomocysteinelevelsinneonatalcalveswithdiarrhea
AT cumaliozkan evaluationofhomocysteinelevelsinneonatalcalveswithdiarrhea
AT edanurokman evaluationofhomocysteinelevelsinneonatalcalveswithdiarrhea