Myoepithelioma of soft tissue

Myoepitheliomas and mixed tumors involving deep subcutaneous and subfascial soft tissues of limb or limb girdle are rare lesions as against salivary lesions that are well established conditions. Here, we report a 22-year-old female who presented with painful hard swelling in the left gluteal region...

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Main Authors: Pai Mukhta, Naik Ramadas, Kamath Ramachandra, Magar Dilasma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=100;epage=102;aulast=Pai
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author Pai Mukhta
Naik Ramadas
Kamath Ramachandra
Magar Dilasma
author_facet Pai Mukhta
Naik Ramadas
Kamath Ramachandra
Magar Dilasma
author_sort Pai Mukhta
collection DOAJ
description Myoepitheliomas and mixed tumors involving deep subcutaneous and subfascial soft tissues of limb or limb girdle are rare lesions as against salivary lesions that are well established conditions. Here, we report a 22-year-old female who presented with painful hard swelling in the left gluteal region of 1½ year duration. MRI showed a large ill-defined heterogeneous mass lesion measuring about 7-8 cm. in the left sacral region eroding the left sacroiliac region and left sacroiliac joint. With a clinical diagnosis of chondrosarcoma, the tumor with the surrounding tissue was resected in segments at surgery. Histomorphology revealed nests, sheets and cords of round to spindled cells with extensive squamous metaplasia in a myxoid to fibrous stroma. These cells extensively infiltrated muscle and bone. The tumor cells expressed immunoreactivity for cytokeratin (AE1/AE3) and S-100.
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spelling doaj.art-a6d320d9d6a6423083db5d6ee18a4c492022-12-21T17:30:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292009-01-01521100102Myoepithelioma of soft tissuePai MukhtaNaik RamadasKamath RamachandraMagar DilasmaMyoepitheliomas and mixed tumors involving deep subcutaneous and subfascial soft tissues of limb or limb girdle are rare lesions as against salivary lesions that are well established conditions. Here, we report a 22-year-old female who presented with painful hard swelling in the left gluteal region of 1½ year duration. MRI showed a large ill-defined heterogeneous mass lesion measuring about 7-8 cm. in the left sacral region eroding the left sacroiliac region and left sacroiliac joint. With a clinical diagnosis of chondrosarcoma, the tumor with the surrounding tissue was resected in segments at surgery. Histomorphology revealed nests, sheets and cords of round to spindled cells with extensive squamous metaplasia in a myxoid to fibrous stroma. These cells extensively infiltrated muscle and bone. The tumor cells expressed immunoreactivity for cytokeratin (AE1/AE3) and S-100.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=100;epage=102;aulast=PaiMixed tumormyoepitheliomasoft tissue
spellingShingle Pai Mukhta
Naik Ramadas
Kamath Ramachandra
Magar Dilasma
Myoepithelioma of soft tissue
Indian Journal of Pathology and Microbiology
Mixed tumor
myoepithelioma
soft tissue
title Myoepithelioma of soft tissue
title_full Myoepithelioma of soft tissue
title_fullStr Myoepithelioma of soft tissue
title_full_unstemmed Myoepithelioma of soft tissue
title_short Myoepithelioma of soft tissue
title_sort myoepithelioma of soft tissue
topic Mixed tumor
myoepithelioma
soft tissue
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=100;epage=102;aulast=Pai
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AT naikramadas myoepitheliomaofsofttissue
AT kamathramachandra myoepitheliomaofsofttissue
AT magardilasma myoepitheliomaofsofttissue