Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain

Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain

Abstract Aging-related tau astrogliopathy (ARTAG) describes tau pathology in astrocytes in different locations and anatomical regions. In the present study we addressed the question of whether sequential distribution patterns can be recognized for ARTAG or astroglial tau pathologies in both primary...

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Bibliographic Details
Main Authors: Gabor G. Kovacs, Sharon X. Xie, John L. Robinson, Edward B. Lee, Douglas H. Smith, Theresa Schuck, Virginia M.-Y. Lee, John Q. Trojanowski
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Aging-related tau astrogliopathy
ARTAG
Astrocytic plaque
Brain barrier
Hierarchical involvement
Tufted astrocyte
Online Access:http://link.springer.com/article/10.1186/s40478-018-0552-y

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