Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation

Introduction:Crocus sativus (saffron) is widely used in China, Iran, and India for dyeing and as a food additive and medicinal plant. Safranal, as one of the main constituents of saffron, is responsible for its aroma and has been reported to have anticancer, antioxidant, and anti-inflammation proper...

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Bibliographic Details
Main Authors: Peeraphong Lertnimitphun, Yiwen Jiang, Nami Kim, Wenwei Fu, Changwu Zheng, Hongsheng Tan, Hua Zhou, Xue Zhang, Weizhong Pei, Yue Lu, Hongxi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
Crocus sativus
saffron
safranal
macrophages
MAPKs
NF-κB
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01281/full

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