Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer
Edible/medicinal mushrooms have been traditionally used in Asian countries either in the cuisine or as dietary supplements and nutraceuticals. In recent decades, they have aroused increasing attention in Europe as well, due to their health and nutritional benefits. In particular, among the different...
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MDPI AG
2023-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/12/10120 |
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| author | Marzia Bruna Gariboldi Emanuela Marras Nicole Ferrario Veronica Vivona Pamela Prini Francesca Vignati Gianpaolo Perletti |
| author_facet | Marzia Bruna Gariboldi Emanuela Marras Nicole Ferrario Veronica Vivona Pamela Prini Francesca Vignati Gianpaolo Perletti |
| author_sort | Marzia Bruna Gariboldi |
| collection | DOAJ |
| description | Edible/medicinal mushrooms have been traditionally used in Asian countries either in the cuisine or as dietary supplements and nutraceuticals. In recent decades, they have aroused increasing attention in Europe as well, due to their health and nutritional benefits. In particular, among the different pharmacological activities reported (antibacterial, anti-inflammatory, antioxidative, antiviral, immunomodulating, antidiabetic, etc.), edible/medicinal mushrooms have been shown to exert in vitro and in vivo anticancer effects on several kinds of tumors, including breast cancer. In this article, we reviewed mushrooms showing antineoplastic activity again breast cancer cells, especially focusing on the possible bioactive compounds involved and their mechanisms of action. In particular, the following mushrooms have been considered: <i>Agaricus bisporus</i>, <i>Antrodia cinnamomea</i>, <i>Cordyceps sinensis</i>, <i>Cordyceps militaris</i>, <i>Coriolus versicolor</i>, <i>Ganoderma lucidum</i>, <i>Grifola frondosa</i>, <i>Lentinula edodes</i>, and <i>Pleurotus ostreatus</i>. We also report insights into the relationship between dietary consumption of edible mushrooms and breast cancer risk, and the results of clinical studies and meta-analyses focusing on the effects of fungal extracts on breast cancer patients. |
| first_indexed | 2024-03-11T02:21:43Z |
| format | Article |
| id | doaj.art-a6d9a1494c2a4599b07c48546431b969 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T02:21:43Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-a6d9a1494c2a4599b07c48546431b9692023-11-18T10:48:56ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-06-0124121012010.3390/ijms241210120Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast CancerMarzia Bruna Gariboldi0Emanuela Marras1Nicole Ferrario2Veronica Vivona3Pamela Prini4Francesca Vignati5Gianpaolo Perletti6Department of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyDepartment of Biotechnology and Life Sciences (DBSV), University of Insubria, 21100 Varese, ItalyEdible/medicinal mushrooms have been traditionally used in Asian countries either in the cuisine or as dietary supplements and nutraceuticals. In recent decades, they have aroused increasing attention in Europe as well, due to their health and nutritional benefits. In particular, among the different pharmacological activities reported (antibacterial, anti-inflammatory, antioxidative, antiviral, immunomodulating, antidiabetic, etc.), edible/medicinal mushrooms have been shown to exert in vitro and in vivo anticancer effects on several kinds of tumors, including breast cancer. In this article, we reviewed mushrooms showing antineoplastic activity again breast cancer cells, especially focusing on the possible bioactive compounds involved and their mechanisms of action. In particular, the following mushrooms have been considered: <i>Agaricus bisporus</i>, <i>Antrodia cinnamomea</i>, <i>Cordyceps sinensis</i>, <i>Cordyceps militaris</i>, <i>Coriolus versicolor</i>, <i>Ganoderma lucidum</i>, <i>Grifola frondosa</i>, <i>Lentinula edodes</i>, and <i>Pleurotus ostreatus</i>. We also report insights into the relationship between dietary consumption of edible mushrooms and breast cancer risk, and the results of clinical studies and meta-analyses focusing on the effects of fungal extracts on breast cancer patients.https://www.mdpi.com/1422-0067/24/12/10120breast canceredible/medicinal mushroomsin vitro studiesin vivo studiesclinical studies |
| spellingShingle | Marzia Bruna Gariboldi Emanuela Marras Nicole Ferrario Veronica Vivona Pamela Prini Francesca Vignati Gianpaolo Perletti Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer International Journal of Molecular Sciences breast cancer edible/medicinal mushrooms in vitro studies in vivo studies clinical studies |
| title | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
| title_full | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
| title_fullStr | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
| title_full_unstemmed | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
| title_short | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
| title_sort | anti cancer potential of edible medicinal mushrooms in breast cancer |
| topic | breast cancer edible/medicinal mushrooms in vitro studies in vivo studies clinical studies |
| url | https://www.mdpi.com/1422-0067/24/12/10120 |
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