Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada
This study describes the association between dietary patterns and prostate cancer (PCa) risk in a population-based case-control study conducted in Montreal, Canada (2005–2012). Cases (<i>n</i> = 1919) were histologically confirmed, aged ≤75 years. Concomitantly, controls (<i>n</...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/12/7/1907 |
| _version_ | 1797564028845817856 |
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| author | Karine Trudeau Marie-Claude Rousseau Christine Barul Ilona Csizmadi Marie-Élise Parent |
| author_facet | Karine Trudeau Marie-Claude Rousseau Christine Barul Ilona Csizmadi Marie-Élise Parent |
| author_sort | Karine Trudeau |
| collection | DOAJ |
| description | This study describes the association between dietary patterns and prostate cancer (PCa) risk in a population-based case-control study conducted in Montreal, Canada (2005–2012). Cases (<i>n</i> = 1919) were histologically confirmed, aged ≤75 years. Concomitantly, controls (<i>n</i> = 1991) were randomly selected from the electoral list and frequency-matched to cases by age (±5 years). During face-to-face interviews, a 63-item food frequency questionnaire focusing on the two years before diagnosis/interview was administered. Three dietary patterns were identified from principal component analysis. Unconditional logistic regression estimated the association between dietary patterns and PCa, adjusting for age, ethnicity, education, family history, and timing of last PCa screening. When comparing scores in the highest vs. lowest quartiles, the Healthy Eating pattern was associated with a decreased risk of overall PCa (Odds ratio (OR) = 0.76, 95% confidence interval (CI) = 0.61, 0.93); this association was stronger for high-grade cancers (OR = 0.66, 95% CI = 0.48, 0.89). By contrast, the Western Sweet and Beverages pattern was associated with an elevated risk of overall PCa (OR = 1.35, 95% CI = 1.10, 1.66). The Western Salty and Alcohol pattern was not associated with PCa risk. These findings suggest that some dietary patterns influence PCa development. |
| first_indexed | 2024-03-10T18:51:36Z |
| format | Article |
| id | doaj.art-a6dff000304d44c0b642dbe0ba699d3a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T18:51:36Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-a6dff000304d44c0b642dbe0ba699d3a2023-11-20T05:08:06ZengMDPI AGNutrients2072-66432020-06-01127190710.3390/nu12071907Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, CanadaKarine Trudeau0Marie-Claude Rousseau1Christine Barul2Ilona Csizmadi3Marie-Élise Parent4Epidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique, University of Quebec, Laval, QC H7V 1B7, CanadaEpidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique, University of Quebec, Laval, QC H7V 1B7, CanadaEpidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique, University of Quebec, Laval, QC H7V 1B7, CanadaDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USAEpidemiology and Biostatistics Unit, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique, University of Quebec, Laval, QC H7V 1B7, CanadaThis study describes the association between dietary patterns and prostate cancer (PCa) risk in a population-based case-control study conducted in Montreal, Canada (2005–2012). Cases (<i>n</i> = 1919) were histologically confirmed, aged ≤75 years. Concomitantly, controls (<i>n</i> = 1991) were randomly selected from the electoral list and frequency-matched to cases by age (±5 years). During face-to-face interviews, a 63-item food frequency questionnaire focusing on the two years before diagnosis/interview was administered. Three dietary patterns were identified from principal component analysis. Unconditional logistic regression estimated the association between dietary patterns and PCa, adjusting for age, ethnicity, education, family history, and timing of last PCa screening. When comparing scores in the highest vs. lowest quartiles, the Healthy Eating pattern was associated with a decreased risk of overall PCa (Odds ratio (OR) = 0.76, 95% confidence interval (CI) = 0.61, 0.93); this association was stronger for high-grade cancers (OR = 0.66, 95% CI = 0.48, 0.89). By contrast, the Western Sweet and Beverages pattern was associated with an elevated risk of overall PCa (OR = 1.35, 95% CI = 1.10, 1.66). The Western Salty and Alcohol pattern was not associated with PCa risk. These findings suggest that some dietary patterns influence PCa development.https://www.mdpi.com/2072-6643/12/7/1907prostate cancercase-control studydietary patternsHealthy Eating patternWestern Salty and Alcohol patternWestern Sweet and Beverages pattern |
| spellingShingle | Karine Trudeau Marie-Claude Rousseau Christine Barul Ilona Csizmadi Marie-Élise Parent Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada Nutrients prostate cancer case-control study dietary patterns Healthy Eating pattern Western Salty and Alcohol pattern Western Sweet and Beverages pattern |
| title | Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada |
| title_full | Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada |
| title_fullStr | Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada |
| title_full_unstemmed | Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada |
| title_short | Dietary Patterns Are Associated with Risk of Prostate Cancer in a Population-Based Case-Control Study in Montreal, Canada |
| title_sort | dietary patterns are associated with risk of prostate cancer in a population based case control study in montreal canada |
| topic | prostate cancer case-control study dietary patterns Healthy Eating pattern Western Salty and Alcohol pattern Western Sweet and Beverages pattern |
| url | https://www.mdpi.com/2072-6643/12/7/1907 |
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