BMP-2 releasing mineral-coated microparticle-integrated hydrogel system for enhanced bone regeneration
Introduction: Large bone defects (LBD) caused by trauma, infection, and tumor resection remain a significant clinical challenge. Although therapeutic agents such as bone morphogenetic protein-2 (BMP-2), have shown substantial potency in various clinical scenarios, their uncontrollable release kineti...
Main Authors: | Hongwei Xu, Huanhuan Luo, Jiayu Chen, Gang Chen, Xiaohua Yu, Zhaoming Ye |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1217335/full |
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