PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS

<strong>Abstract. </strong>Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the...

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Main Authors: O. A. Gizinger, I. I. Dolgushin
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
Online Access:http://mimmun.ru/index.php/mimmun/article/view/651
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author O. A. Gizinger
I. I. Dolgushin
author_facet O. A. Gizinger
I. I. Dolgushin
author_sort O. A. Gizinger
collection DOAJ
description <strong>Abstract. </strong>Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in females with urogenital trichomoniasis has been studied in comparison with these values in healthy females. It has been established that infected females have increased levels of IL-1α, IL-1β, RAIL-1, TNFα, IL-8, while IFN-γ concentration is decreased. The obtained results enable to get a deeper insight into the cytokine-mediated reactions in the local immunity system of genital tracts in case of trichomoniasis.
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spelling doaj.art-a6e26dcfc70f4fb4bbb32958ad94d2272023-09-03T14:01:18ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0175–660160410.15789/1563-0625-2005-5–6-601-604648PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASISO. A. Gizinger0I. I. Dolgushin1НИИ иммунологии Челябинской государственной медицинской академии МУЗ, Кожно–венерологический диспансер №1 , г.ЧелябинскНИИ иммунологии Челябинской государственной медицинской академии МУЗ, Кожно–венерологический диспансер №1 , г.Челябинск<strong>Abstract. </strong>Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in females with urogenital trichomoniasis has been studied in comparison with these values in healthy females. It has been established that infected females have increased levels of IL-1α, IL-1β, RAIL-1, TNFα, IL-8, while IFN-γ concentration is decreased. The obtained results enable to get a deeper insight into the cytokine-mediated reactions in the local immunity system of genital tracts in case of trichomoniasis.http://mimmun.ru/index.php/mimmun/article/view/651local immunity systemurogenital trichomoniasisvaginal secretioncytokines
spellingShingle O. A. Gizinger
I. I. Dolgushin
PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
Медицинская иммунология
local immunity system
urogenital trichomoniasis
vaginal secretion
cytokines
title PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_full PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_fullStr PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_full_unstemmed PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_short PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_sort proinflammatory cytokines profile in women with genitourinary trichomoniasis
topic local immunity system
urogenital trichomoniasis
vaginal secretion
cytokines
url http://mimmun.ru/index.php/mimmun/article/view/651
work_keys_str_mv AT oagizinger proinflammatorycytokinesprofileinwomenwithgenitourinarytrichomoniasis
AT iidolgushin proinflammatorycytokinesprofileinwomenwithgenitourinarytrichomoniasis