Generation of iPSC lines with SLC16A2:G401R or SLC16A2 knock out

Generation of iPSC lines with SLC16A2:G401R or SLC16A2 knock out

The X-linked Allan-Herndon-Dudley syndrome (AHDS) is characterized by severely impaired psychomotor development and is caused by mutations in the SLC16A2 gene encoding the thyroid hormone transporter MCT8 (monocarboxylate transporter 8). By targeting exon 3 of SLC16A2 using CRISPR/Cas9 with single-s...

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Bibliographic Details
Main Authors: Katarzyna Anna Ludwik, Robert Opitz, Sabine Jyrch, Matthias Megges, January Weiner, Dieter Beule, Peter Kühnen, Harald Stachelscheid
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Stem Cell Research
Subjects:
Allan-Herndon-Dudley syndrome
SLC16A2
MCT8
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123002428

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http://www.sciencedirect.com/science/article/pii/S1873506123002428

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