Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking

Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking

Viniferifuran was investigated for its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme catalyzing xanthine to uric acid. An enzyme kinetics analysis showed that viniferifuran possessed a strong inhibition on XO in a typical anti-competitive manner with an IC<sub>50<...

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Bibliographic Details
Main Authors: Yaxin Yang, Qian Chen, Shiyang Ruan, Junli Ao, Shang-Gao Liao
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
viniferifuran
xanthine oxidase
inhibition mechanism
Online Access:https://www.mdpi.com/1420-3049/27/22/7730

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