A Simple Eco-Friendly HPLC-PDA Method for the Simultaneous Determination of Paclitaxel and Seliciclib in Plasma Samples for Assessing Their Pharmacodynamics and Pharmacokinetics in Combination Therapy for Uterine Sarcoma

<i>Background/Objectives</i>: Uterine sarcoma, a rare cancer originating in the smooth muscle of the uterus, exhibits high rates of recurrence and metastasis. It represents one of the most challenging types of cancer due to its chemorefractory nature, showing little response to conventio...

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Bibliographic Details
Main Authors: Amsha S. Alsegiani, Sarah Alrubia, Ibrahim A. Darwish
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/60/10/1601