Role of RNA Polymerase II Promoter-Proximal Pausing in Viral Transcription

The promoter-proximal pause induced by the binding of the DRB sensitivity-inducing factor (DSIF) and the negative elongation factor (NELF) to RNAP II is a key step in the regulation of metazoan gene expression. It helps maintain a permissive chromatin landscape and ensures a quick transcriptional re...

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Bibliographic Details
Main Authors: Marilyn Whelan, Martin Pelchat
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/9/2029