FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW

Objective: To increase the detection rate of preterm preeclampsia (PE) first trimester combined screening tests are being developed. The aim of this review is to create an overview of the currently investigated screening markers, algorithms and their validations. Methods: Comprehensive review of the...

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Main Authors: Beatrice Mosimann, Sofia K. Amylidi-Mohr, Daniel Surbek, Luigi Raio
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Hypertension in Pregnancy
Subjects:
Online Access:http://dx.doi.org/10.1080/10641955.2019.1682009
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author Beatrice Mosimann
Sofia K. Amylidi-Mohr
Daniel Surbek
Luigi Raio
author_facet Beatrice Mosimann
Sofia K. Amylidi-Mohr
Daniel Surbek
Luigi Raio
author_sort Beatrice Mosimann
collection DOAJ
description Objective: To increase the detection rate of preterm preeclampsia (PE) first trimester combined screening tests are being developed. The aim of this review is to create an overview of the currently investigated screening markers, algorithms and their validations. Methods: Comprehensive review of the literature concerning first trimester screening for PE Results and conclusions: Studies investigating a total of 160 biochemical, 6 biophysical and 14 ultrasound markers could be identified. Of the 21 algorithms published, mainly the algorithm published by the Fetal Medicine Foundation London has been validated. This algorithm performes significantly better than screening by anamnestic risk factors only.
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spelling doaj.art-a6f379f6e2604a7d9cc138888171aa532023-09-19T09:24:43ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652020-01-0139111110.1080/10641955.2019.16820091682009FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEWBeatrice Mosimann0Sofia K. Amylidi-Mohr1Daniel Surbek2Luigi Raio3University Hospital, University of BernUniversity Hospital, University of BernUniversity Hospital, University of BernUniversity Hospital, University of BernObjective: To increase the detection rate of preterm preeclampsia (PE) first trimester combined screening tests are being developed. The aim of this review is to create an overview of the currently investigated screening markers, algorithms and their validations. Methods: Comprehensive review of the literature concerning first trimester screening for PE Results and conclusions: Studies investigating a total of 160 biochemical, 6 biophysical and 14 ultrasound markers could be identified. Of the 21 algorithms published, mainly the algorithm published by the Fetal Medicine Foundation London has been validated. This algorithm performes significantly better than screening by anamnestic risk factors only.http://dx.doi.org/10.1080/10641955.2019.1682009first trimester screeningpreeclampsiacombined screening
spellingShingle Beatrice Mosimann
Sofia K. Amylidi-Mohr
Daniel Surbek
Luigi Raio
FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
Hypertension in Pregnancy
first trimester screening
preeclampsia
combined screening
title FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
title_full FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
title_fullStr FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
title_full_unstemmed FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
title_short FIRST TRIMESTER SCREENING FOR PREECLAMPSIA – A SYSTEMATIC REVIEW
title_sort first trimester screening for preeclampsia a systematic review
topic first trimester screening
preeclampsia
combined screening
url http://dx.doi.org/10.1080/10641955.2019.1682009
work_keys_str_mv AT beatricemosimann firsttrimesterscreeningforpreeclampsiaasystematicreview
AT sofiakamylidimohr firsttrimesterscreeningforpreeclampsiaasystematicreview
AT danielsurbek firsttrimesterscreeningforpreeclampsiaasystematicreview
AT luigiraio firsttrimesterscreeningforpreeclampsiaasystematicreview