Direct deoxygenative borylation of carboxylic acids
Converting a carboxylic acid into a boronic acid, which makes a useful chemical handle from a feedstock chemical, currently relies on decarboxylation and requires metal catalysts and prior functionalization. Here the authors show a simplified procedure via deoxygenation, using diboron and free carbo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-25229-8 |
| _version_ | 1818994084504666112 |
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| author | Jianbin Li Chia-Yu Huang Mohamad Ataya Rustam Z. Khaliullin Chao-Jun Li |
| author_facet | Jianbin Li Chia-Yu Huang Mohamad Ataya Rustam Z. Khaliullin Chao-Jun Li |
| author_sort | Jianbin Li |
| collection | DOAJ |
| description | Converting a carboxylic acid into a boronic acid, which makes a useful chemical handle from a feedstock chemical, currently relies on decarboxylation and requires metal catalysts and prior functionalization. Here the authors show a simplified procedure via deoxygenation, using diboron and free carboxylic acids. |
| first_indexed | 2024-12-20T20:52:20Z |
| format | Article |
| id | doaj.art-a6f4905c22944a00aa2c69ecf7ace295 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T20:52:20Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-a6f4905c22944a00aa2c69ecf7ace2952022-12-21T19:26:54ZengNature PortfolioNature Communications2041-17232021-08-011211910.1038/s41467-021-25229-8Direct deoxygenative borylation of carboxylic acidsJianbin Li0Chia-Yu Huang1Mohamad Ataya2Rustam Z. Khaliullin3Chao-Jun Li4Department of Chemistry, McGill UniversityDepartment of Chemistry, McGill UniversityDepartment of Chemistry, McGill UniversityDepartment of Chemistry, McGill UniversityDepartment of Chemistry, McGill UniversityConverting a carboxylic acid into a boronic acid, which makes a useful chemical handle from a feedstock chemical, currently relies on decarboxylation and requires metal catalysts and prior functionalization. Here the authors show a simplified procedure via deoxygenation, using diboron and free carboxylic acids.https://doi.org/10.1038/s41467-021-25229-8 |
| spellingShingle | Jianbin Li Chia-Yu Huang Mohamad Ataya Rustam Z. Khaliullin Chao-Jun Li Direct deoxygenative borylation of carboxylic acids Nature Communications |
| title | Direct deoxygenative borylation of carboxylic acids |
| title_full | Direct deoxygenative borylation of carboxylic acids |
| title_fullStr | Direct deoxygenative borylation of carboxylic acids |
| title_full_unstemmed | Direct deoxygenative borylation of carboxylic acids |
| title_short | Direct deoxygenative borylation of carboxylic acids |
| title_sort | direct deoxygenative borylation of carboxylic acids |
| url | https://doi.org/10.1038/s41467-021-25229-8 |
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