Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis

Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis

Accumulating evidence from both animal and human studies suggests that activation of beige fat increases cellular energy expenditure, ultimately reducing adiposity. Here, we report the central role of adipocyte-derived lysyl oxidase (Lox) in the formation of thermogenic beige fat. Mice exposed to co...

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Bibliographic Details
Main Authors: Chun Xing, Duo Jiang, Yang Liu, Qiqun Tang, Haiyan Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-01-01
Series:Genes and Diseases
Subjects:
Adaptive thermogenesis
BAT
Beige fat
Lysyl oxidase
TNFα
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301264

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