Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage
Abstract Introduction The association between prediabetes and functional outcome in cerebrovascular diseases is controversial. No study has explored the relationship between prediabetes and functional outcome in intracerebral hemorrhage patients. Our study aimed to explore the association between pr...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-04-01
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| Series: | Brain and Behavior |
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| Online Access: | https://doi.org/10.1002/brb3.1530 |
| _version_ | 1818966931082838016 |
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| author | Qiongzhang Wang Guiqian Huang Fei Chen Pinglang Hu Wenwei Ren Xiaoqian Luan ChengYe Zhou Jincai He |
| author_facet | Qiongzhang Wang Guiqian Huang Fei Chen Pinglang Hu Wenwei Ren Xiaoqian Luan ChengYe Zhou Jincai He |
| author_sort | Qiongzhang Wang |
| collection | DOAJ |
| description | Abstract Introduction The association between prediabetes and functional outcome in cerebrovascular diseases is controversial. No study has explored the relationship between prediabetes and functional outcome in intracerebral hemorrhage patients. Our study aimed to explore the association between prediabetes and functional outcome in intracerebral hemorrhage patients 1 month poststroke. Methods One hundred and fifty intracerebral hemorrhage patients were consecutively recruited within the first 24 hr after admission and were followed up for 1 month. Patients were divided into a diabetes mellitus group, a prediabetes group, and a nondiabetic group by fasting glucose levels, 2‐hr postprandial blood glucose levels, and glycosylated hemoglobin levels. Patients with modified Rankin Scale scores >2 at 1 month were defined as having a poor functional outcome. Results The prediabetes group had a higher risk of poor functional outcome than the nondiabetic group in intracerebral hemorrhage patients (37.9% vs. 9.8%, χ2 = 11.521, p = .001). According to the logistic regression analyses, prediabetes was associated with a poor functional outcome in intracerebral hemorrhage patients after adjusting for confounding factors (odds ratio = 6.167, 95% confidence interval = 1.403–27.102, p = .016). Conclusions Our findings show that prediabetes is associated with a poor functional outcome in intracerebral hemorrhage patients 1 month poststroke. |
| first_indexed | 2024-12-20T13:40:44Z |
| format | Article |
| id | doaj.art-a6f70e3b6fe34257a21691263a58f7a5 |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-12-20T13:40:44Z |
| publishDate | 2020-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-a6f70e3b6fe34257a21691263a58f7a52022-12-21T19:38:50ZengWileyBrain and Behavior2162-32792020-04-01104n/an/a10.1002/brb3.1530Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhageQiongzhang Wang0Guiqian Huang1Fei Chen2Pinglang Hu3Wenwei Ren4Xiaoqian Luan5ChengYe Zhou6Jincai He7Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The Deqing People's Hospital Huzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaDepartment of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang ChinaAbstract Introduction The association between prediabetes and functional outcome in cerebrovascular diseases is controversial. No study has explored the relationship between prediabetes and functional outcome in intracerebral hemorrhage patients. Our study aimed to explore the association between prediabetes and functional outcome in intracerebral hemorrhage patients 1 month poststroke. Methods One hundred and fifty intracerebral hemorrhage patients were consecutively recruited within the first 24 hr after admission and were followed up for 1 month. Patients were divided into a diabetes mellitus group, a prediabetes group, and a nondiabetic group by fasting glucose levels, 2‐hr postprandial blood glucose levels, and glycosylated hemoglobin levels. Patients with modified Rankin Scale scores >2 at 1 month were defined as having a poor functional outcome. Results The prediabetes group had a higher risk of poor functional outcome than the nondiabetic group in intracerebral hemorrhage patients (37.9% vs. 9.8%, χ2 = 11.521, p = .001). According to the logistic regression analyses, prediabetes was associated with a poor functional outcome in intracerebral hemorrhage patients after adjusting for confounding factors (odds ratio = 6.167, 95% confidence interval = 1.403–27.102, p = .016). Conclusions Our findings show that prediabetes is associated with a poor functional outcome in intracerebral hemorrhage patients 1 month poststroke.https://doi.org/10.1002/brb3.1530diabetes mellitusfunctional outcomeintracerebral hemorrhageprediabetes |
| spellingShingle | Qiongzhang Wang Guiqian Huang Fei Chen Pinglang Hu Wenwei Ren Xiaoqian Luan ChengYe Zhou Jincai He Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage Brain and Behavior diabetes mellitus functional outcome intracerebral hemorrhage prediabetes |
| title | Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| title_full | Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| title_fullStr | Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| title_full_unstemmed | Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| title_short | Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| title_sort | prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage |
| topic | diabetes mellitus functional outcome intracerebral hemorrhage prediabetes |
| url | https://doi.org/10.1002/brb3.1530 |
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