One-Carbon and Polyamine Metabolism as Cancer Therapy Targets

One-Carbon and Polyamine Metabolism as Cancer Therapy Targets

Cancer metabolic reprogramming is essential for maintaining cancer cell survival and rapid replication. A common target of this metabolic reprogramming is one-carbon metabolism which is notable for its function in DNA synthesis, protein and DNA methylation, and antioxidant production. Polyamines are...

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Bibliographic Details
Main Authors: Anowarul Islam, Zeeshan Shaukat, Rashid Hussain, Stephen L. Gregory
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomolecules
Subjects:
methionine
one-carbon metabolism
polyamines
cancer
metabolic therapy
reactive oxygen species
Online Access:https://www.mdpi.com/2218-273X/12/12/1902

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