Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

<p>Abstract</p> <p>Background</p> <p>The clinical implication of Ras/Raf/ERK pathway activity in breast cancer tissue and its association with response to chemotherapy is controversial. We aimed to explore the value of p90RSK phosphorylation, a downstram molecule of the...

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Main Authors: Moon Hyeong-Gon, Yi Jae, Kim Hee, Lee Hea, Lee Kyung-Min, Yi Minju, Ahn Sookyung, Shin Hee-Chul, Ju Ji-hyun, Shin Incheol, Han Wonshik, Noh Dong-Young
Format: Article
Jezik:English
Izdano: BMC 2012-12-01
Serija:BMC Cancer
Teme:
Breast cancer
P90RSK
Chemotherapy
Predictive marker
ERK
Estrogen receptor
Online dostop:http://www.biomedcentral.com/1471-2407/12/585

Internet

http://www.biomedcentral.com/1471-2407/12/585

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