Engraftment of allogeneic iPS cell-derived cartilage organoid in a primate model of articular cartilage defect

Engraftment of allogeneic iPS cell-derived cartilage organoid in a primate model of articular cartilage defect

Allogeneic iPSC-derived cartilage organoids survive and integrate with surrounding native cartilage without immune reactions in a primate model of chondral defects in the knee joints, being remodeled and functioning as articular cartilage.

Bibliographic Details
Main Authors:	Kengo Abe, Akihiro Yamashita, Miho Morioka, Nanao Horike, Yoshiaki Takei, Saeko Koyamatsu, Keisuke Okita, Shuichi Matsuda, Noriyuki Tsumaki
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-36408-0

Similar Items

Regeneration of joint surface defects by transplantation of allogeneic cartilage: application of iPS cell-derived cartilage and immunogenicity
by: Kengo Abe, et al.
Published: (2023-11-01)

Considerations in hiPSC-derived cartilage for articular cartilage repair
by: Akihiro Yamashita, et al.
Published: (2018-10-01)

Destruction and regeneration in bone and cartilage
by: Noriyuki Tsumaki
Published: (2023-12-01)

Chondrocyte-like cells in nucleus pulposus and articular chondrocytes have similar transcriptomic profiles and are paracrine-regulated by hedgehog from notochordal cells and subchondral bone
by: Hiroki Hagizawa, et al.
Published: (2023-05-01)

Articular cartilage /
by: Athanasiou, K. A. (Kyriacos A.)
Published: (c201)

ARTICULAR CARTILAGE /
by: Athanasiou, K. A. (Kyriacos A.), author, et al.
Published: (2017)

Cartilage organoids for cartilage development and cartilage-associated disease modeling
by: Weiping Lin, et al.
Published: (2023-01-01)

Imaging of articular cartilage
by: Bhawan K Paunipagar, et al.
Published: (2014-08-01)

Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage
by: Zelong Dou, et al.
Published: (2021-04-01)

Cryopreservation of human articular cartilage
by: Xia, Z, et al.
Published: (2005)

Articular Cartilage Regeneration in Osteoarthritis
by: Livia Roseti, et al.
Published: (2019-10-01)

The minor collagens in articular cartilage
by: Yunyun Luo, et al.
Published: (2017-02-01)

Inhibition of metalloproteinases in articular cartilage
by: Stinn, Jennifer L. (Jennifer Leigh)
Published: (2007)

The superficial zone of articular cartilage
by: Taku Saito
Published: (2022-05-01)

INJURED ARTICULAR CARTILAGE REPAIR
by: Ariana Barlič, et al.
Published: (2008-02-01)

Patophysiology of articular cartilage in elderly
by: Fabbriciani C, et al.
Published: (2010-05-01)

Control of articular synovitis for bone and cartilage regeneration in rheumatoid arthritis
by: Hiromu Ito, et al.
Published: (2018-04-01)

Effects of rapid cooling on articular cartilage.
by: Guan, J, et al.
Published: (2006)

Complications in orthopaedics : articular cartilage restoration /
by: Cole, Brian J. 276762, et al.
Published: (2011)

New trends in articular cartilage repair
by: Magali Cucchiarini, et al.
Published: (2015-01-01)

Submicroscopic structure of canine articular cartilage
by: D. Horky, et al.
Published: (2004-06-01)

Electrokinetic evaluation of human articular cartilage
by: Lin, John W. (John Wei-Chieh)
Published: (2007)

Strategies for Articular Cartilage Repair and Regeneration
by: Yanxi Liu, et al.
Published: (2021-12-01)

Articular Cartilage Regeneration through Bioassembling Spherical Micro-Cartilage Building Blocks
by: Brian E. Grottkau, et al.
Published: (2022-10-01)

Quantitative Arthroscopic Assessment of Articular Cartilage Quality by Means of Cartilage Electromechanical Properties
by: Tomas Mickevicius, M.D., et al.
Published: (2018-07-01)

Allogenic chondrocyte/osteoblast-loaded β-tricalcium phosphate bioceramic scaffolds for articular cartilage defect treatment
by: Shuai Wu, et al.
Published: (2019-12-01)

Boosting cartilage repair with silk fibroin-DNA hydrogel-based cartilage organoid precursor
by: Congyi Shen, et al.
Published: (2024-05-01)

Effects of Electrical Stimulation on Articular Cartilage Regeneration with a Focus on Piezoelectric Biomaterials for Articular Cartilage Tissue Repair and Engineering
by: Zhengjie Zhou, et al.
Published: (2023-01-01)

In vivo cartilage regeneration in a multi-layered articular cartilage architecture mimicking scaffold
by: Karthikeyan Rajagopal, et al.
Published: (2020-09-01)

Bovine articular cartilage decellularized matrix as a scaffold for use in cartilage tissue engineering
by: Amin Tavassoli, et al.
Published: (2012-09-01)

Comparative Outcomes for Treatment of Articular Cartilage Lesions in the Ankle with Particulated Juvenile Cartilage Allograft
by: James Deal MD, BS, et al.
Published: (2017-09-01)

Lyophilized allogeneic costal cartilage graft for septorhinoplasty
by: Jin Sup Eom, et al.
Published: (2023-10-01)

Cartilage Restoration Using Dehydrated Allogeneic Cartilage, Platelet-Rich Plasma, and Autologous Cartilage Mixture Sealed With Activated Autologous Serum
by: Tracy M. Tauro, B.S., B.A., et al.
Published: (2020-06-01)

Influence of cyclic loading on the nutrition of articular cartilage.
by: O'Hara, B, et al.
Published: (1990)

Mechanoadaptation: articular cartilage through thick and thin
by: Vincent, T, et al.
Published: (2018)

What makes the permanent articular cartilage permanent?
by: Murphy, C
Published: (2011)

Surgical management of articular cartilage defects in the knee /
by: 276762 Cole, Brian J., et al.
Published: (2009)

Computational study of mechanical properties of articular cartilage /
by: Erwan Siddiq Asyraf Ahmad Hariri, 1991-, author 605206, et al.
Published: (2014)

Articular cartilage repair biomaterials: strategies and applications
by: Mingkai Wang, et al.
Published: (2024-02-01)

Advancements in tissue engineering for articular cartilage regeneration
by: Maohua Chen, et al.
Published: (2024-02-01)