Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression

Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression

Abstract Background There is an increasing interest in utilizing tau PET to identify patients early in Alzheimer’s disease (AD). In this work, a temporal lobe composite (Eτ) volume of interest (VOI) was evaluated in a longitudinal flortaucipir cohort and compared to a previously described global neo...

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Bibliographic Details
Main Authors: Vikas Kotari, Sudeepti Southekal, Michael Navitsky, Ian A. Kennedy, Ming Lu, Amanda Morris, Jennifer Ann Zimmer, Adam S. Fleisher, Mark A. Mintun, Michael D. Devous, Michael J. Pontecorvo
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Alzheimer’s Research & Therapy
Online Access:https://doi.org/10.1186/s13195-023-01160-6

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