The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration
Cannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal cannabis regulations worldwide, the study of cannabinoids, both endogenous and exogenous, has similarly flourished in more recent decades. In particular, research investiga...
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Format: | Article |
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MDPI AG
2021-02-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/22/4/2103 |
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author | Tristyn L. Clarke Rachael L. Johnson Jonathan J. Simone Robert L. Carlone |
author_facet | Tristyn L. Clarke Rachael L. Johnson Jonathan J. Simone Robert L. Carlone |
author_sort | Tristyn L. Clarke |
collection | DOAJ |
description | Cannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal cannabis regulations worldwide, the study of cannabinoids, both endogenous and exogenous, has similarly flourished in more recent decades. In particular, research investigating the role of cannabinoids in regeneration and neurodevelopment has yielded promising results in vertebrate models. However, regeneration-competent vertebrates are few, whereas a myriad of invertebrate species have been established as superb models for regeneration. As such, this review aims to provide a comprehensive summary of the endocannabinoid system, with a focus on current advances in the area of endocannabinoid system contributions to invertebrate neurodevelopment and regeneration. |
first_indexed | 2024-03-09T00:41:52Z |
format | Article |
id | doaj.art-a700ac9825664fabb784a555b81685a0 |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-09T00:41:52Z |
publishDate | 2021-02-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-a700ac9825664fabb784a555b81685a02023-12-11T17:48:53ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-02-01224210310.3390/ijms22042103The Endocannabinoid System and Invertebrate Neurodevelopment and RegenerationTristyn L. Clarke0Rachael L. Johnson1Jonathan J. Simone2Robert L. Carlone3Department of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, CanadaDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, CanadaDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, CanadaDepartment of Biological Sciences, Brock University, 1812 Sir Isaac brock Way, St. Catharines, ON L2S 3A1, CanadaCannabis has long been used for its medicinal and psychoactive properties. With the relatively new adoption of formal medicinal cannabis regulations worldwide, the study of cannabinoids, both endogenous and exogenous, has similarly flourished in more recent decades. In particular, research investigating the role of cannabinoids in regeneration and neurodevelopment has yielded promising results in vertebrate models. However, regeneration-competent vertebrates are few, whereas a myriad of invertebrate species have been established as superb models for regeneration. As such, this review aims to provide a comprehensive summary of the endocannabinoid system, with a focus on current advances in the area of endocannabinoid system contributions to invertebrate neurodevelopment and regeneration.https://www.mdpi.com/1422-0067/22/4/2103AEA2-AGCB1CB2endocannabinoidregeneration |
spellingShingle | Tristyn L. Clarke Rachael L. Johnson Jonathan J. Simone Robert L. Carlone The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration International Journal of Molecular Sciences AEA 2-AG CB1 CB2 endocannabinoid regeneration |
title | The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration |
title_full | The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration |
title_fullStr | The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration |
title_full_unstemmed | The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration |
title_short | The Endocannabinoid System and Invertebrate Neurodevelopment and Regeneration |
title_sort | endocannabinoid system and invertebrate neurodevelopment and regeneration |
topic | AEA 2-AG CB1 CB2 endocannabinoid regeneration |
url | https://www.mdpi.com/1422-0067/22/4/2103 |
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