Natural Killer Cells Promote Kidney Graft Rejection Independently of Cyclosporine A Therapy

Natural Killer Cells Promote Kidney Graft Rejection Independently of Cyclosporine A Therapy

Natural Killer (NK) cells have recently been recognized as key players in antibody-mediated chronic allograft failure, thus requiring a comprehensive understanding whether NK cells can escape conventional immunosuppressive regimens. Influence of cyclosporine A (CyA) on NK cell function was studied i...

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Bibliographic Details
Main Authors: Muhammad Imtiaz Ashraf, Attia Sarwar, Anja A. Kühl, Elena Hunger, Arne Sattler, Felix Aigner, Heinz Regele, Martina Sauter, Karin Klingel, Stefan Schneeberger, Thomas Resch, Katja Kotsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
Natural Killer (NK) cells
cyclosporine A
graft rejection
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02279/full

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