The Cytoprotective Effects of Baicalein on H<sub>2</sub>O<sub>2</sub>-Induced ROS by Maintaining Mitochondrial Homeostasis and Cellular Tight Junction in HaCaT Keratinocytes

The Cytoprotective Effects of Baicalein on H<sub>2</sub>O<sub>2</sub>-Induced ROS by Maintaining Mitochondrial Homeostasis and Cellular Tight Junction in HaCaT Keratinocytes

Reactive oxygen species (ROS) promote oxidative stress, which directly causes molecular damage and disrupts cellular homeostasis, leading to skin aging. Baicalein, a flavonoid compound isolated from the root of <i>Scutellaria baicalensis Georgi</i> has antioxidant, anticancer, anti-infla...

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Bibliographic Details
Main Authors: Gyeonghyeon Kim, Dong-Wook Han, Jong Hun Lee
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
baicalein
antioxidants
tight junction
mitochondrial homeostasis
Nrf2/NQO-1/HO-1 pathway
HaCaT keratinocytes
Online Access:https://www.mdpi.com/2076-3921/12/4/902

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